lymphadenopathy Flashcards
where produces lymphoid cells
marrow and thymus
what are secondary lymphoid tissues
lymph nodes, spleen , liver, tonsils
do lymph nodes have valves
yes
what lymphocyte is assoc with follicles and germinal centres
b -cells
where are plasma cells mainly found
in medulla of node
what cells in lymph node do autoimmune conditions and infection predominantly stimulate
b -cells
vascular supply and drainage from spleen
supply - splenich artery -coeliac axis
drainage - splenich vein - SMV
what is the spleen formed of
red pulp and white pulp
what does the red pulp of the spleen consist of
sinusoids and cords
what is found within cords of red pulp
macrophages and fibroblasts
what is the white pulp made of
peri-arteroilar lymphoid sheaths- PALS
cd4 and lymphoid cells
symtoms of splenomegaly
dragging sensation
discomfort when eating
pain if infarction
hypersplenism triad
what is hypersplenism triad
splenomegaly
decrease in one or more blood component
correction by splenectomy
most common cause of hyposplenism
splenectomy
what is seen on blood film in hyposplenism
howell jolly bodies