haemopoiesis Flashcards

1
Q

types of white blood cells

A

granulocytes
monocytes
lymphocytes

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2
Q

what is the nucleated precursor between myeloblast and neutrophil

A

myleocytes

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3
Q

what are the development events of haemopoiesis

A
self renewal 
proliferation
differentiation 
maturation
apoptosis
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4
Q

what cells are affected in a myeloid cancer

A

RBC
granulocytes
monocytes

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5
Q

what germ layer do stem cells originate from

A

mesoderm

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6
Q

when are the first circulating projinators seen

A

as early as week 5

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7
Q

what is the first site of erythroid activity and when does it stop here

A

yolk sac stops at week 10

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8
Q

when does the liver start haemopoiesis in embryo

A

starts by week 6

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9
Q

when does the bone marrow start haemopoiesis in embryo

A

by week 16

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10
Q

where is marrow sampled from in adult

A

posterior illiac crest

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11
Q

where is marrow sampled in child

A

tibial marrow

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12
Q

what regulaets megakaryocyte development and what produces it

A

thrombopoietin and liver- thrombocytopenia in liver disease

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13
Q

what test is used to identify lineage

A

immunophenotyping

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14
Q

what type of cells is immunophenotyping used for

A

lymphoid cells

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