Lung disease- alveolar disease Flashcards

1
Q

List 4 clinical signs of pulmonary parenchymal disease

A

Increased inspiratory/expiratory effort
+/- cough
+/- hemoptysis (coughing up blood) - not that common
Collapse/syncope or cyanosis

Sometimes see minimal signs even though severe pathology present (esp cats)

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2
Q

Define haemoptysis

A

coughing up blood

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3
Q

Where are cough receptors present: alveoli or airways

A

airways
there are no cough receptors in the alveoli

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4
Q

What do crackles on lung ausultation tell you

A

that air is being dragged through fluid

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5
Q

List 5 clinical signs of aspirations pneumonia

A

cough
harsh/ reduced lung sounds
tachypnoea
pyrexia
check oxygenation

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6
Q

Where does aspiration pneumonia commonly like to occur

A

in the cranial lung lobes
common in patients that have been vomiting

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7
Q

What do radiographs show when we have aspirational pneumonia

A

alveolar infiltrate (patchy or focal)

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8
Q

How to you confirm diagnosis of aspiration pneumonia

A

BAL- cytology, check for neutrophils/ toxic neutrophils

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9
Q

You suspect aspiration pneumonia and confirm the diagnosis with BAL and cytology. What antibiotics will you treat with?

A

Ideally based on C and S
Broad spectrum antibiotics as often not sure what we’re dealing with
Need to penetrate, dissolve in blood-bronchus barrier- lipophilic antibiotics penetrate this best

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10
Q

List 7 Examples of alveolar disease

A

Aspiration pneumonia
pulmonary oedema (cardio vs non-cardio)
pulmonary haemorrhage
eosinophilic lung disease
pulmonary parasites
pulmonary neoplasia- primary/ metastatic
infectious pneumonias

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11
Q

Describe how you would treat aspiration pneumonia

A

supportive care: oxygen therapy, antibiotics
Treat any underlying cause
Consider anti-acid medication if frequent occurence
Metoclopramide to improve motility and increase lower oesophageal sphincter tone

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12
Q

What is pulmonary oedema

A

when there is fluid accumulation in the interstitium and subsequently in the alveoli at a rate that exceeds removal

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13
Q

What (physiologic) conditions can pulmonary oedema be a consequence of

A

Increase hydrostatic pressure
reduced oncotic pressure
increased vascular permeability
impaired lymphatic drainage

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14
Q

What are the two types of pulmonary oedema and what types of fluid are formed in each?

A

Cardiogenic - due to increased hydrostatic pressure; fluid is building up behind the failing heart - fluid formed is low-protein

Non-cardiogenic - the result of lung damage that increases vascular permeability and so protein leaks out - fluid formed is high protein

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15
Q

List 6 Possible causes of non-cardiogenic pulmonary oedema

A

most commonly: pulmonary epithelial injury
Choking
Near-drowning
Electric shock
Head trauma
smoke inhalation
SIRS

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16
Q

Describe the damage caused by a physical lung injury and how you would approach treatment

A

pulmonary contusion- ventilation perfusion mismatch
chest wall damage and pain

supportive care with oxygen supplementation ASAP
stabilisation of thoracic wall
analgesia

17
Q

T/F eosinophilic lung disease will cause alveolar signs

A

True

18
Q

what is the signalment of eosinophilic lung disease

A

typically young adults

19
Q

how to do you diagnose eosinophilic lung disease

A

BAL
radiographs show diffuse bronchointerstitial pattern

20
Q

how do you treat eosinophilic lung disease

A

prednisolone 1-2mg/kg daily

21
Q

What antibiotic would you select to treat mycoplasma infection

A

Doxycycline

22
Q

What is the name of the heartworm in dogs

A

Angiostronglylus vasorum

23
Q

where do dogs get A. Vasorum from

A

Ingest L3 in snail/slug

24
Q

where do A. Vasorum become adults in the dog

A

pulmonary artery

25
Q

Clinical signs of A. Vasorum

A

breathlessness/ cough
bleeding- coagulopathies
neuro signs

26
Q

How to diagnose A.Vasorum

A

May need to take a number of samples before getting a positive result
L1 in faeces (flotation techniques)
L1 in BAL fluid
L1 in faeces - dectected by smear methods

27
Q

Treatment of A. Vasorum

A

anthelminitics= imidacloprid and moxidectin (advocate), or milbemycin
supportive treatment= bronchodilators, corticosteroids, cage rest, O2 therapy