Lung Cancers Flashcards

1
Q

pneumonic “coin” lesion on X-ray film or noncalcified nodule on CT

A

Lung Cancer

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2
Q

Lung Cancer complications

A

SPHERE: SVC Syndrome; Pancoast tumor; Horner Syndrome; Endocrine (paraneoplastic); Recurrent Laryngeal Symptoms (hoarseness); Effusions (pleural or pericardial)

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3
Q

Central Lung Cancers

A

Squamous and Small Cell Carcinomas

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4
Q

Most common lung cancer in nonsmokers

A

Adenocarcinoma Lung CA

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5
Q

Location of Adenocarcinoma Lung CA

A

Peripheral

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6
Q

Activating mutations associated with Adenocarcinoma Lung CA

A

k-ras; EGFR and ALK

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7
Q

Hypertrophic osteoarthropathy (clubbing)

A

Adenocarcinoma Lung CA

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8
Q

Lung cancer that grows along alceolar septa causing apparent thickening of alveolar walls

A

Adenocarcinoma Lung CA

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9
Q

Keratin pearls and intercellular bridges

A

Squamous Cell Carcinoma of Lung

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10
Q

Cancer that may produce ACTH, ADH, or antibodies against presynaptic calcium channels (Lambert-Eaton)

A

Small Cell (oat cell) Carcinomar

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11
Q

Cavitation, Cigarettes, hyperCalcemia

A

Squamous Cell Carcinoma of Lung

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12
Q

Produces PTHrP

A

Squamous Cell Carcinoma of Lung

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13
Q

Kulchitsky cells

A

small dark blue cells; associated with Small cell (oat cell) carcinoma

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14
Q

Pleomorphic giant cells found in ther Periphery of lung (occasionally central lung)

A

Large cell carcinoma

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15
Q

Chromogranin A (+)

A

Bronchial carcinoid tumor; it stains Nest of neuroendocrine cells

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16
Q

Carcinoid Syndrome

A

Serotonin secretion; flushing, diarrhea, wheezing

17
Q

Tx of carcinoid Syndrome

A

Octreotide; somtostatin analog

18
Q

Malignancy of the pleura associated with asbestos

A

Mesothelioma

19
Q

Result of Mesothelioma

A

hemorrhagic pleural effusions and pleural thickening

20
Q

Carcinoma that affects the apex of the lung

A

Pancoast tumor

21
Q

IL ptosis, miosis, and anhidrosis

A

Horner Syndrome; if Pancoast tumor compresses the cervical sympathetic plexus; SVC syndrome; sensorimotor deficits and hoarseness

22
Q

Pacial Plethora

A

SVC syndrome, impaired blood drainage from head

23
Q

1 area lung cancers like to metastasize to

A

Adrenals