Lung Cancer Flashcards

1
Q

Risk factors in long cancer?

A

Smoking
Asbestos
Metal Exposure

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2
Q

Describe the different ways lung cancer can present? (Eg: Form of lung cancer)

A

Primary Tumour
Local Invasion
Metastases - Lymph + Blood
Systemic Effects

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3
Q

What are the symptoms?

A

Haemoptysis
Recurrent Pneumonia
Stridor

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4
Q

Clinical Signs of Local Invasion? (Signs and Explanation)

A

Hoarse voice due to invasion of the recurrent laryngeal nerve
AF due to invasion of the pericardium
Pericardial Effusion due to pericardial invasion
Dysphagia caused by local invasion of the Oesophagus
Weakness of the arm caused by invasion of the brachial plexus by Pancoast tumour
Pleural effusion caused by local invasion of the pleural cavity

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5
Q

Clinical Signs of Local Invasion

A
Hoarse Voice
AF
Pleural Effusion
Pericardial Effusion
Dysphagia
Arm Weakness
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6
Q

Common sites for metastases?

A
Liver
Lung 
Bone
Skin
Adrenal
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7
Q

Describe brain metastases from Lung Cancer?

A

Comes on slowly, presents as visual weakness and headaches (Worse in the morning)
‘Ring enhancing lesion’

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8
Q

Describe liver metastases from Lung Cancer?

A

Normally painless

Can present as obstructive jaundice

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9
Q

Describe bone metastases from lung cancer?

A

Low impact injuries cause fractures

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10
Q

Describe left adrenal metastases from Lung cancer?

A

May cause a hormonal effect

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11
Q

Describe the paraneoplastic effects of Lung Cancer?

A

Clubbing
Thrombophelbitis
Weight Loss
Hypertrophic Pulmonary Osteoparthy

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12
Q

Investigations for Lung cancer?

A

FBC
CXR
CT Scan
Bronchoscopy and Biopsy

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13
Q

Describe a classical presentation of lung cancer?

A

SMOKER PRESENTS WITH HAEMOPYTSIS, WEIGHT LOSS AND AN ABNORMAL CXR

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14
Q

Describe the two ways that lung cancer can present?

A

Benign, Malignant and Mesastases (Very common)

Rare) (Common

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15
Q

What are the types of Cancer tumour?

A

Adenocarcinoma
Squamous Carcinoma
Small Cell Carcinoma

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16
Q

Describe squamous cell carcinoma

A

Most likely to Cavitate
Central Lung Lesion
Secretes PTH
This causes Hypocalcaemia

17
Q

Describe Adenocarcinoma

A

Originates from glands
May cavitate
Peripheral
More common in non smokers

18
Q

Describe small cell cancer?

A

High mortality
Central Lung Lesion
Secretes ATCH

19
Q

Which type of tumour is most likely to capitate?

A

Squamous followed by Adenocarccinoma

20
Q

Most common in non smokers

A

Adenocarcinoma

21
Q

Most common centrally?

A

Squamous and Small Cell

22
Q

Most common peripherally?

A

Adenocarcinoma

23
Q

Secretes ATCH

A

Small Cell Carcinoma

24
Q

Secretes PTH

A

Squamous Cell Carcinoma

25
Q

Treatment for Lung Cancer?

A

Surgery, Chemotherapy, Radiotherapy

26
Q

Indications for Surgery?

A

Non Small Cell Cancer
Localised
QofL