long term control of blood pressure Flashcards
where is renin produced
from the juxtaglomerular (granule cells)of the kidney
what triggers renin production (3 things)
activation of sympathetic nerves to the juxtaglomerular apparatus
decreased distension of afferent arterioles (the ‘renal baroreflex’)
decreased delivery of Na/Cl through the tubule
what does renin do
converts angiotensin to angiotensin I
what converts angiotensin I to angiotensin II
ACE -(angiotensin converting enzyme)
what does angiotensin II do
stimulates release of aldosterone
what does aldosterone do
increases Na re absorption
increases release of ADH from the pituitary
its a vasoconstrictor
where is ADH produced
synthesized in the hypothalamus released from the posterior pituitary
what triggers ADH release? (3 things)
decrease in blood volume
increase in osmolarity of interstitial fluid
circulating angiotensin II
what is another name for ADH
vassopressin
what does ADH do
increases permeability of the collecting duct to water so water goes back into the blood
causes vasoconstriction
where is ANP produced and released
produced in, and released from the myocardial cells in the atria
what triggers ANP release
increased distension of the atria
what does ANP do
increases excretion of Na
inhibits the release of renin
acts on medullary CV centers to reduce MAP
what does essential (primary) hypertension mean
hypertension of unknown cause
