long term control of blood pressure Flashcards

1
Q

where is renin produced

A

from the juxtaglomerular (granule cells)of the kidney

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2
Q

what triggers renin production (3 things)

A

activation of sympathetic nerves to the juxtaglomerular apparatus
decreased distension of afferent arterioles (the ‘renal baroreflex’)
decreased delivery of Na/Cl through the tubule

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3
Q

what does renin do

A

converts angiotensin to angiotensin I

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4
Q

what converts angiotensin I to angiotensin II

A

ACE -(angiotensin converting enzyme)

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5
Q

what does angiotensin II do

A

stimulates release of aldosterone

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6
Q

what does aldosterone do

A

increases Na re absorption
increases release of ADH from the pituitary
its a vasoconstrictor

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7
Q

where is ADH produced

A

synthesized in the hypothalamus released from the posterior pituitary

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8
Q

what triggers ADH release? (3 things)

A

decrease in blood volume
increase in osmolarity of interstitial fluid
circulating angiotensin II

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9
Q

what is another name for ADH

A

vassopressin

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10
Q

what does ADH do

A

increases permeability of the collecting duct to water so water goes back into the blood
causes vasoconstriction

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11
Q

where is ANP produced and released

A

produced in, and released from the myocardial cells in the atria

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12
Q

what triggers ANP release

A

increased distension of the atria

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13
Q

what does ANP do

A

increases excretion of Na
inhibits the release of renin
acts on medullary CV centers to reduce MAP

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14
Q

what does essential (primary) hypertension mean

A

hypertension of unknown cause

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