Arrhythmia-Therapy Flashcards
what is the general mechanism of class I drugs
fast sodium channel blockers
name a class Ia drug
disopyramide
what is the action of Disopyramide
blocks sodium channels
delay repolarisation
increases the action potential duration
what can Disopyramide be used to treat
A-fib
PAC
PVC
VT
name a class Ib drug
phenytonin
what is the action of phenytonin
blocks sodium channels
accelerates depolarization
decreases action potential duration
what can phenytonin be used to treat
ventricular dysrhythmias: PVC, VT, V-fib
name a class Ic drug
Flecainide
what is the mechanism of Flecainide
blocks sodium channels
little effect on AP or repolarisation
what is Flecainide used to treat
severe ventricular dysrhythmias
(may be used for Afib /flutter
what are the class II drugs
Beta blockers
class II drugs are first line for what arrhythmia
atria fibrillation
what beta blocker is used for a fib
Bisoprolol
name a class III drug
amiodarone
what is the mechanism of class III drugs (amiodarone)
increase action potential duration
prolong repolarisation
what can amiodarone be used to treat
arhhythmias that are difficult to treat
life threatening VT or fibrillation
atrial fib/flutter that is resistant to other drugs
what type of drugs are the class IV
CCB
name a class IV drug
verapamil
what can verapamil be used to treat
SVT
rate control of atrial flutter/fib
digoxin works by inhibiting what
the NA/K ATPase pump
what type of drug can digoxin be described as
positive inotrope
what is digoxin used to treat
CHF
Atrial fib/flutter
what has to be monitored in Digoxin use
K levels
drug levels
what are the signs of digoxin toxicity
vomiting Xanthopsia Bradycardia Tachycardia Arrhythmias -VT VF
what is Amiodarone used for
VT
what does Amiodarone interact with
many drugs particulary digoxin
what are the side effects of Aminodarone
thyroid problems
pulmonary fibrosis
grey pigmentation appearance
corneal deposits
What is the action of adenosine
slows conduction through the AV node
what is Adenosine commonly used to treat
(paroxysmal) supraventricular tachycardia
what can warfarin interact with
marcolide antibiotics
antifungals
anti-epileptic drugs
