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cardiovascular system > Arrhythmia-Therapy > Flashcards

Arrhythmia-Therapy Flashcards

1
Q

what is the general mechanism of class I drugs

A

fast sodium channel blockers

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2
Q

name a class Ia drug

A

disopyramide

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3
Q

what is the action of Disopyramide

A

blocks sodium channels
delay repolarisation
increases the action potential duration

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4
Q

what can Disopyramide be used to treat

A

A-fib
PAC
PVC
VT

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5
Q

name a class Ib drug

A

phenytonin

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6
Q

what is the action of phenytonin

A

blocks sodium channels
accelerates depolarization
decreases action potential duration

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7
Q

what can phenytonin be used to treat

A

ventricular dysrhythmias: PVC, VT, V-fib

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8
Q

name a class Ic drug

A

Flecainide

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9
Q

what is the mechanism of Flecainide

A

blocks sodium channels

little effect on AP or repolarisation

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10
Q

what is Flecainide used to treat

A

severe ventricular dysrhythmias

(may be used for Afib /flutter

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11
Q

what are the class II drugs

A

Beta blockers

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12
Q

class II drugs are first line for what arrhythmia

A

atria fibrillation

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13
Q

what beta blocker is used for a fib

A

Bisoprolol

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14
Q

name a class III drug

A

amiodarone

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15
Q

what is the mechanism of class III drugs (amiodarone)

A

increase action potential duration

prolong repolarisation

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16
Q

what can amiodarone be used to treat

A

arhhythmias that are difficult to treat
life threatening VT or fibrillation
atrial fib/flutter that is resistant to other drugs

17
Q

what type of drugs are the class IV

A

CCB

18
Q

name a class IV drug

A

verapamil

19
Q

what can verapamil be used to treat

A

SVT

rate control of atrial flutter/fib

20
Q

digoxin works by inhibiting what

A

the NA/K ATPase pump

21
Q

what type of drug can digoxin be described as

A

positive inotrope

22
Q

what is digoxin used to treat

A

CHF

Atrial fib/flutter

23
Q

what has to be monitored in Digoxin use

A

K levels

drug levels

24
Q

what are the signs of digoxin toxicity

A 
vomiting 
Xanthopsia
Bradycardia
Tachycardia 
Arrhythmias -VT VF
25
Q

what is Amiodarone used for

A

VT

26
Q

what does Amiodarone interact with

A

many drugs particulary digoxin

27
Q

what are the side effects of Aminodarone

A

thyroid problems
pulmonary fibrosis
grey pigmentation appearance
corneal deposits

28
Q

What is the action of adenosine

A

slows conduction through the AV node

29
Q

what is Adenosine commonly used to treat

A

(paroxysmal) supraventricular tachycardia

30
Q

what can warfarin interact with

A

marcolide antibiotics
antifungals
anti-epileptic drugs

cardiovascular system (34 decks)

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