liver Flashcards

biliary anatomy: recall the anatomy of the biliary system and embryological origins

1
Q

where does the biliary tree start

A

millions of bile canaliculi adjacent to hepatocytes

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2
Q

what do canaliculi drain into

A

small ductules, then into small bile ducts

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3
Q

what do small bile ducts coalesce to form

A

larger bile ducts for each liver segment

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4
Q

what do larger bile ducts merge to form

A

right and left hepatic ducts

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5
Q

what do right and left hepatic ducts converge to form

A

common hepatic duct

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6
Q

what is connected to common hepatic duct

A

cystic duct

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7
Q

function of cystic duct

A

connect gall bladder to biliary tree

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8
Q

what do the common hepatic duct and cystic duct merge to form

A

common bile duct

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9
Q

where does the common bile duct extend towards

A

duodenum

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10
Q

what joins the common bile duct distally, and what does this form

A

pancreatic duct, forming ampulla of Vater

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11
Q

where does the ampulla of Vater open up into medial wall of duodenum

A

duodenal papilla

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12
Q

when does the gut tube start to develop

A

day 29-34

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13
Q

what 2 layers of germline tissue form gut tube

A

endoderm (inner layer), mesoderm (outer layer)

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14
Q

function of mesoderm

A

wraps around to provide structural and functional support

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15
Q

fate of endoderm

A

liver develops from foregut endoderm; mucosal epithelium, mucosal glands, submucosal glands

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16
Q

fate of mesoderm

A

liver bud breaches into connective tissue mesoderm; lamina propria, gut smooth muscle, blood vessels, serosa

17
Q

what arise from neural crest

A

submucosal and myenteric plexuses

18
Q

what also start to develop at day 29-34

A

connective tissue, hepatoblasts

19
Q

what happens at day 40-55

A

liver begins to take shape; gall bladder and biliary ducts are distinguishable