alimentary disease Flashcards
signs and symptoms: recall and explain common signs and symptoms of gastrointestinal and liver diseases
define sign
externally visible and detectable to someone other than the patient
define symptom
internally experienced by patient and impossible to detect by others
signs of general GI disease
malaise, rapid weight loss (unintentional and uncontrollable), anorexia (eating disorder), anaemia
define malaise
non-specific; generally unwell from indeterminable cause
define anaemia and common causes
reduced ability to carry oxygen due to low [Hb]; fewer normal sized erythrocytes or normal number smaller erythrocytes
hepatobiliary disorders
right-upper quadrant pain, biliary colic, jaundice, dark urine, pale stool, ascites
why right-upper quadrant pain
where most of liver and gall bladder located
what does right-upper quadrant pain suggest
hepatobiliary disease
define biliary colic and cause
colicky (severe windy) pain caused by gall bladder contraction against downstream obstruction
in biliary colic what could the obstruction be
gall stones, impingement of common bile duct (e.g. by tumour)
define jaundice and cause
hallmark symptom of liver failure caused by increase in circulating bilirubin
signs of jaundice
yellowing of skin, sclera and mucous membranes
why is circulating bilirubin increased in jaundice
hepatobiliary system unable to process amount of bilirubin in blood for pre-hepatic, hepatic or post-hepatic reasons
what causes dark urine
elevated conjugated bilirubin in urine, associated with liver disease
why does stool become pale in liver disease
bilirubin doesn’t male it to gut so stercobilin concentration, which causes pigmentation of faeces, will decrease
define ascites
generalised oedema of >30mL in abdominal cavity
what causes ascites
cancer, malnutrition, liver failure
disorders of upper GI tract
haemoptysis, melaena, nausea, vomiting, haematemesis, dysphagia, odynophagia, heartburn, acid regurgitation, belching, chest pain, epigastric pain
define haemoptysis
coughing up blood (GI or respiratory disease)
define malaena and cause
black tarry stool due to upper GI bleeding, with pigment altered by gut flora, digestive enzymes and secretions
define nausea
queeziness with/without inclincation to vomit
define vomiting (emesis)
voluntary/involuntary rapid ejection of stomach contents
define haematemesis
vomitting blood
define dysphagia
difficulty in swallowing food, fluid
define odynophagia
pain during swallowing food, fluid
define heartburn and common cause
central burning sensation, acid regurgitation
define acid regurgitation
process of stomach acid entering oesophagus
define belching
voluntarily/involuntarily excess air in stomach escaping through mouth
define chest pain
perception of discomfort in central chest pain
causes of chest pain
referred pain, or not; includes heartburn
define epigastric pain
discomfort in central upper abdomen
mid-GI tract disorders
abdominal pain, steatorrhoea, diarrhoea, abdominal distension
define abdominal pain
pain experienced superficial to abdominal cavity
what can abdominal pain be sub-categorised into
4 quadrants/9 regions
define steatorrhoea
sloppy, oily faeces caused by excess fats in stool
in steatorrhoea, what causes excess fats in stool
digestive failure due to reduced lipase activity or reduced bile activity
define diarrhoea
very watery faeces and frequent defecation
define abdominal distension
general presentation of large abdomen
causes of abdominal distenstion
harmful excess gas in colon, ascites, abdominal tumour
lower-GI tract disorders
abdominal pain, rectal bleeding, constipation, diarrhoea, incontinence, flatulence
cause of rectal bleeding
hasn’t been in GI system long enough to lose oxygen and have Hb broken down
define constipation
irregular passing of stools regularly, or inability to completely empty bowel
in constipation, why is stool firmer and dryer
reduced gut motility allowing for water reabsoprtion and dehydration of faeces
define incontinence
loss of voluntary control over excretion of waste (bladder, rectum)
causes of incontinence
neural damage to anal sphincters, mechanical damage to sphincters, associated diarrhoea too watery to retain
characteristics of flatulence
loudness, frequency or severity of smell
whole body disorders caused by GI disorders
cachexia, obesity, lymphadenopathy, jaundice
define cachexia and demographic prevalence
muscle wasting, often moe common in older adults preceding decline in physical functioning
define obesity
overt sign of nutritional imbalance
cause of obesity
extended period of positive eating balance leading to storage in subcutaneous white adipose tissue
define lymphadenopathy
palpable enlargement of lymphoid tissue (uni/bilateral)
hand disorders caused by GI disorders
koilonychia, leuconychia, nail clubbing, Dupytren’s contracture, tachycardia, tremor
define koilonychia
spooning of nails of fingers (concave in centre)
cause of koilonychia
iron-deficient anaemia
define leuconychia
partial/complete whitening of nails
cause of leuconychia
dietary nutrient deficiency
define nail clubbing
nails of fingers take an enlarged, concave appearance
causes of nail clubbing
malabsorption, Crohn’s, cirrhosis
assessing nail clubbing
assess angle of nail bed with distal phalange; <160, >180
define Dupytren’s contracture
one or more fingers into bent position (usually ring, little finger)
cause of Dupytren’s contracture
thickened cords of skin develop in layer of tissue under skin of palm
in Dupytren’s contracture, what are thickened cords of skin associated with
persistent uncontrolled diabetes, excess alcohol consumption
define tremor
inability to keep hand completely still
abdominal signs of GI disorder
palpable organ enlargement, abdominal tenderness, distension
cause and presentation of hepatomegaly
hepatitis, palpated in upper right quadrant
causes of abdominal tenderness
local obstruction, infection
anus and rectum signs of GI disorder
haemorrhoids, fistula, fissure, proctitis
define haemorrhoids (piles)
swollen superficial blood vessels prone to bleeding (can feel itchy)
2 types of haemorrhoid and name painful one
internal, external; external is painful
define fistula
generic term for alternative pathway; any pathway from anus/rectum to outside environment not directly through entire anal canal
define fissure
tear or ulceration of mucosal lining of peri-anal tissue; prone to infection
define proctitis
inflammation of inside of rectum
2 methods to detect proctitis
digital rectal exam, sigmoidoscopy
define subjectivity
differences in perception or location of pain between individuals
factor influencing interpretability
referred pain
9 regions of regional abdominal pain
right hypochronriac pain, epigastric pain, left hypochondriac pain, right lumbar (flank) pain, umbillical pain, left lumbar (flank) pain, right iliac (inguinal) pain, hypogastric (suprapubic) pain, left iliac (inguinal) pain
3 key factors to determining problem
history, examination, investigations
investigating and reporting pain: SOCRATES
Site, Onset, Character, Radiation, Associated symptoms, Timing, Exacerbating/relieving symptoms, Severity