Liver Flashcards
Widespread fibrotic (scarred) bands of connective tissue
Tissue becomes nodular
Nodules block blood flow and lymph
Liver shrinks and hardens
Cirrhosis
Laennec’s cirrhosis is caused by
Alcoholism
______ a rare autoimmune disease that slowly destroys the liver’s bile ducts. This causes bile and other toxins to build up in the liver, a condition known as cholestasis.
The inflammation and scarring of the bile ducts can lead to cirrhosis
Biliary (cirrhosis)
Ascites is…
Fluid in the peritoneal space
Portal hypertension
Ascites
Esophageal varices
Biliary obstruction
Hepatic Encephalopathy
Are all complications of…
Cirrhosis
Biliary obstruction =
Lower
Bile, Vit. K, Clotting Factors
Which has an increased risk for…
Bleeding
Pruritus….
Itching
Hep B, C, D
NAFLD (Obesity)
Alcohol use
Contribute to
Cirrhosis
Why is employment history important to a health history
Exposure to toxins
Esophageal varices usually develop when blood flow to the liver is blocked. They often occur in people with advanced liver disease.
Usually there are no symptoms
Symptoms include vomiting blood, tar-like or bloody stools, and, in severe cases, shock.
Treatments include
This medicine ____
Medical procedures to stop bleeding, and, in rare cases, liver transplant
Beta blockers
Lactate dehydrogenase (LDH) is …
an enzyme that helps the body convert glucose (sugar) from food into usable energy for cells
Cirrhosis has this effect on
AST, ALT, LDH
Alkaline phosphate
GGT
Serum bilirubin
Ammonia
Increase
Norms
AST 10 - 36
ALT 4 - 36 alanine transaminase
LDH 140 - 280
ALP 44 - 146
Serum Bilirubin <1mg/dl
Ammonia < 30
Cirrhosis has this affect on
Albumin
Platelets
Hgb
Hct
RBC
Lower
Norms
Albumin 3.5 - 5.3
Platelets 150,000 and 450,000 microliter of blood
Hgb 12 - 17
Hct 36 - 50
RBC: 4 - 6 million
US transient elastography (TE) is….
Ultrasound elastography or FibroScan, is a non-invasive method that uses ultrasound to measure liver stiffness
EGD & ERCP may be used to test for cirrhosis
T or F
T
EGD esophagastroduodeno
Endoscopic retrograde cholangiopancreatography (ERCP) is a procedure that uses an endoscope and X-rays to examine and treat problems with the bile and pancreatic ducts
Why pruritis from cirrhosis
Increased serum bilirubin & jaundice
Why acute confusion from cirrhosis
Increased ammonia level
Alcohol withdrawal
How can a hemorrhage occur from cirrhosis
HTN in portal hypertension