Kach: GI Motility Flashcards

1
Q

Laxatives aka _____

Are used to

Prevent straining, before diagnostic procedures, remove poison & Flush helminths from system

A

Cathartic

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2
Q

Types of Laxatives include

Stimulants which…

Bulk Forming

Osmotic Laxatives

Lubricant

A

Chemically irritate the bowels

Increase the size

Pull water into GI tract

Coat and MAKE Gi Tract slippery

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3
Q

____ is the laxative of choice for older adults due to the reduction of cholesterol levels

A

Psyllium

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4
Q

These Laxatives directly stimulate the nerve plexus in internal wall causing increased reflexes.

A

Chemical Stimulants

Bisacodyl (Dulcolax)
Castor oil (generic)
Senna (Senokot)

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5
Q

Bisacodyl (Dulcolax)
Castor oil (generic)
Senna (Senokot)

Which type…

Work how..

A

Chemical Stimulants

Stimulate the nerve plexus in intestine to increase movement

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6
Q

Bisacodyl (Dulcolax)
Castor oil (generic)
Senna (Senokot)

How long do these Laxatives take to work

A

Castor oil 2 - 6 hrs

Rest 6 - 8 hrs

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7
Q

Contradicted

Acute abdominal disorders
Appendicitis, diverticulitis, bowel obstruction, UC.

Use caution with heart block, CAD

A

Stimulants Laxatives

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8
Q

Adverse effects of Stimulats Laxative
Cathartic dependence

A

Cathartic dependence: Need for Laxative to poop

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9
Q

Mineral oil blocks

A

Absorption of fat

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10
Q

Encopresis

A

A condition in which a child resists having bowel movements, causing impacted stool

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11
Q

Methylcellulose (Citrucel)
Polycarbophil (Fibercon)
Psyllium (Metamucil)

Are which type of Laxatives

A

Bulk forming

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12
Q

Bulk forming Laxatives

Methylcellulose (Citrucel)
Polycarbophil (Fibercon)
Psyllium (Metamucil)

Work by

A

Increase size of fecal matter which helps pull more fluid inside the intestines.

Can also be used to treat diarrhea

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13
Q

This precaution when taking a Bulk Forming Laxatives

A

Drink atleast 8 oz water

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14
Q

Magnesium Sulfate (Epsom Salt)
Magnesium Citrate
Magnesium Hydroxide (Milk of Magnesium)
Lactulose (Constilac, Cholac)
Lactitol
Polyethylene glycol
Sodium picosulfate with Magnesium oxide and Citric Acid

Are this type of medication

That have this effect

A

Osmotic Laxatives

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15
Q

These Laxatives draw more water into the GI tract and stimulate GI motility

A

Osmotic Laxatives

Magnesium Sulfate (Epsom Salt)
Magnesium Citrate
Magnesium Hydroxide (Milk of Magnesium)
Lactulose (Constilac, Cholac)
Lactitol
Polyethylene glycol
Sodium picosulfate with Magnesium oxide and Citric Acid

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16
Q

____ is a saltless osmotic Laxatives that pulls fluid out of the venous system and into the Lumen of the small intestine

A

Lactulose

Used to treat hepatic Encephalopathy Liver Diseases

17
Q

Milk of Magnesia is a combination of these two GI meds

A

Osmotic Laxatives & Antacid

18
Q

Docusate
Glycerin
Mineral oil

Are all these type of medication

When to give these types of medications

A

Lubricants

Hemorrhoids
Recent rectal surgery

19
Q

Docusate

How it works

A

Lubricant

(Colace)

Detergent action on surface of intestine, increasing admixtures of fat & water making stool softer

20
Q

Glycerin is…

A

Lubricant

Hyperosmolar laxative used in suppository form

Evacuate the rectum but not the small intestine

21
Q

Frequent use of _____ can interfere with absorption of vitamins A, D,E, K

A

Mineral oil

Fat soluble

22
Q

Which patient’s should not strain when making a BM

A

Surgery, MI, obstetrical birth

23
Q

Alvimopan (Entereg)
Methylnaltrexone bromide (Relistor)
Naloxegol (Movantik)
Naldemedine (Symproic)

Are these types of medications

A

Opoid Antagonist

Used to make people using opoids poop

24
Q

All opioid Antagonist are indicated to treat opioid induced Constipation with chronic noncancer pain

Except, _____ which is used post bowel resection surgery

A

Alvimopan

25
Q

Generalized GI Stimulants include this medication

A

Metoclopramide (Reglan)

26
Q

For rapid bowel movement use Metoclopramide which is a GI stimulate.

How does it work

A

Blocks dopamine & makes GI cells more sensitive to acetylcholine

27
Q

This type of Laxatives cannot be used by patients with tardive dyskinesia, seizures, or depression due to the development of these issues with this medication

A

Metoclopramide (GI stimulate)

28
Q

Drug interactions

Avoid alcohol- seizures/Sedation
Antipsychotics
MAOI = HTN

A

Metoclopramide

29
Q

Bismuth subsalicylate
Crofelemer (Mytesi)
Loperamide
Opium derivatives

This class of medication

A

Antidiarrheal

30
Q

Antidiarrheal

Slow

Direct action on lining of GI tract to inhibit local reflexes

Direct action on muscles of the GI tract

Action on CNS centers that cause GI spasm and slowing

A

Direct action on lining of GI tract to inhibit local reflexes (bismuth subsalicylate)

Direct action on muscles of the GI tract (loperamide)

Action on CNS centers that cause GI spasm and slowing (opium)

31
Q

Which type of patients in general shouldn’t receive Laxatives

A

Acute GI problems ( -itis)

Blockages

32
Q

Alosetron (Lotronex)
Eluxadoline (Viberzil)

Used to treat

A

IBS with Diarrhea

33
Q

Linaclotide (Linzess)
Lubiprostone (Amitiza)
Plecanatide (Trulance)
Prucaloptide (Motegrity)
Tegaserod (Zelnorm)

Used to treat…

A

IBS

Constipation

34
Q

Linoclotide & plecanatide have this warning

A

Not for use in children

Used to treat IBS Constipation

35
Q

Prucalopride & tegaserod

Treats IBS Constipation

Have these adverse affects

A

Self harm / Suicide

36
Q

Eluxadoline

Treats IBS with diarrhea

Has this adverse side effects

A

Pancreatitis

37
Q

Alosetron & Eluxadoline maybe used to treat ___ associated with IBS.

Lubiprostone can be used to treat ____ related to IBS

A

Alosetron & Eluxadoline maybe used to treat DIARRHEA associated with IBS.

Lubiprostone can be used to treat CONSTIPATION related to IBS