Kach GI Drugs Flashcards

1
Q

Cimetidine (Tagamet HB)
Famotidine (Pepcid AC)
Nizatidine (Axid AR)

Type of medication

Action

High levels can have this side effect

A

H² Antagonist

Block release of Hydrochloric acid

SE Heart arythmia

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2
Q

Gnawing burning pain a few hours after meals

This disease

A

Peptic ulcer

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3
Q

Leading cause of peptic ulcers

A

NSAIDS

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4
Q

This type of drug is used to treat duodenal ulcers
Benign gastric ulcers
GERD
Acid indigestion

A

Histamine ² Antagonist

Cimetidine (Tagamet HB) >12yrs
Famotidine (Pepcid)
Nizatidine (Axid) >12 yrs
Ranitinde (Zantac)

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5
Q

This type of medication is used for relief of GI hyperacidity
Variety of electrolyte issues

A

Antacids

Aluminum salts
Calcium salts
Magnesium salts
Sodium Bicarbonate

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6
Q

Treatment and maintenance of erosive esophagitis.
GERD
H pylori with antibiotics

A

PPI

Dexlansoprazole (Dexilant)
Esomeprazole (Nexium)
Iansoprazole (Prevacid)

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7
Q

Short term treatment of duodenal ulcers

Oral & esophageal ulcers due to radiation

Chemo/sclerotherapy

A

Gi protectants

Sucralfate (Carafate)

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8
Q

Prevention of NSAID induced ulcers in adults at high risk

Terminates Pregnancy

A

Prostaglandin

Misoprostol

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9
Q

Histamine ² Antagonist

Which one to use in a patient with liver disease

A

Nizatidine (Axid)

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10
Q

Adverse effects

Caution in pregnancy
Cardiac arrhythmias
Hypotension
Gynecomastia
Impotenc
Confusion/ Hallucinations

A

Histamine ² Antagonist

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11
Q

Cimetidine (Tagamet) can slow down absorption time of

Anticoagulant
Beta blockers
Lidocaine
Quindine
Theophylline

What type of med is it

A

Histamine ² Antagonist

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12
Q

Acid rebound happens in these types of meds

A

Calcium Antacids

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13
Q

Potential SE of these drugs is related to acid base balance & electrolytes

They also interfer with the absorption of medication due to changing the pH of the stomach

A

Antacids

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14
Q

Adverse affects

Gastric rupture
Systemic Alkalosis (headache, nausea, irritation, weakness, tetany)
Hypokalemia
Gastric acid rebound
DIARRHEA & CONSTIPATION

A

Antacids

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15
Q

Quickest acting PPI

A

Omeprazole Prilosec

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16
Q

SE

Loss strength
Vertigo
Insomnia
Apathy
Dream abnormalities
Dry mouth
Tongue weakness
Rash
Alopecia
Calcium absorption
Cancer

This med

A

PPI

17
Q

Drug interactions

Increase

Benzodiazepine
Phenytoin
Warfin

Decrease
Ketoconazole
Ophylline

Antiviral / antiretroviral

A

PPI

18
Q

Adverse effects of this medication are mostly GI

Constipation being the most common

A

Gastrointestinal protectant

Sucralfate (carafate)

19
Q

Phenytoin, digoxin, Warfarin, fluoroquinolones antibiotics

&

Sucralfate

Have this precaution

A

Administer 2 hrs apart

20
Q

Used to protect the stomach lining.

Inhibits gastric acid secretions & increases bicarbonate

Used to prevent NSAID gastric ulcers

A

Prostaglandin

Misoprostol

21
Q

Emptying of the GI tract before surgery/ diagnosis

Short term treatment of Constipation

A

Chemical Stimulants

Bisacodyl (Dulcolax)
Castor Oil
Senna (Senokot)

22
Q

Treatment of Constipation

A

Bulk forming Laxatives

Methylcellulose (Citrucel)
Polycarbophil (FiberCon)
Psyllium (Metamucil)

23
Q

Short term treatment of Constipation

A

Osmotic Laxatives

Lactitol Pizensy
Lactulose Constilac
Magnesium (citrate, hydroxide, sulfate)

Polyethylene glycol Miralax

24
Q

Docusate (Colace)
Glycerin (Sani-Supp)
Mineral oil

Belong to this group for treatment of Constipation

A

Lubricants

25
Q

Speeds gastrointestinal recovery following surgeries

Treatment of opoid induced Constipation

A

Opiod Antagonist

Alvimopan (Entereg)
Methylnaltrexone bromide
Naloxegol (Movantik)
Naldemedine (Symproic)

26
Q

Used to decreased diarrhea & help Constipation

A

Bulk forming Laxatives

Citrucel
Fibercon
Metamucil

27
Q

Bulk forming Laxatives

Contradictions

A

Acute abdominal disorders

Appendicitis/ acute infections

28
Q

Are Laxatives contradicted with acute surgical abdomen, fecal impaction, intestinal blockage

A

Yes

29
Q

Patients with hemroids / recent rectal surgery require this laxative

A

Lubricant

30
Q

Metoclopramide is a gastrointestinal stimulate.

Used for: GERD, Neausa / Vomiting, promote GI movement

Side effects:

A

Tardive dyskinesia, seizures, depression

31
Q

Treatment of neausa and vomiting associated with surgery

A

Phenothiazines

Suffix - Azine

Promethazine = treatment Motion Sickness

32
Q

Treatment of Neausa and vomiting associated with Chemotherapy

A

5 HT³ Receptor Blockers

Suffix -Tron

Granisetron
Ondansetron
Palonosetron

33
Q

Adverse effects

Neuroleptic malignant syndrome
Tremors
Muscle spasms
Photo sensitive

Pink to brown urine

A

Phenothiazines

Suffix- Azine

Surgery antimetics

34
Q

These antimetics have the SE of

Prolonged QT syndrome

Risk of torsade de Pointes

A

5 HT³ receptor blocker

Suffix - Tron

Ondansetron Zofran