Kach GI Drugs Flashcards
Cimetidine (Tagamet HB)
Famotidine (Pepcid AC)
Nizatidine (Axid AR)
Type of medication
Action
High levels can have this side effect
H² Antagonist
Block release of Hydrochloric acid
SE Heart arythmia
Gnawing burning pain a few hours after meals
This disease
Peptic ulcer
Leading cause of peptic ulcers
NSAIDS
This type of drug is used to treat duodenal ulcers
Benign gastric ulcers
GERD
Acid indigestion
Histamine ² Antagonist
Cimetidine (Tagamet HB) >12yrs
Famotidine (Pepcid)
Nizatidine (Axid) >12 yrs
Ranitinde (Zantac)
This type of medication is used for relief of GI hyperacidity
Variety of electrolyte issues
Antacids
Aluminum salts
Calcium salts
Magnesium salts
Sodium Bicarbonate
Treatment and maintenance of erosive esophagitis.
GERD
H pylori with antibiotics
PPI
Dexlansoprazole (Dexilant)
Esomeprazole (Nexium)
Iansoprazole (Prevacid)
Short term treatment of duodenal ulcers
Oral & esophageal ulcers due to radiation
Chemo/sclerotherapy
Gi protectants
Sucralfate (Carafate)
Prevention of NSAID induced ulcers in adults at high risk
Terminates Pregnancy
Prostaglandin
Misoprostol
Histamine ² Antagonist
Which one to use in a patient with liver disease
Nizatidine (Axid)
Adverse effects
Caution in pregnancy
Cardiac arrhythmias
Hypotension
Gynecomastia
Impotenc
Confusion/ Hallucinations
Histamine ² Antagonist
Cimetidine (Tagamet) can slow down absorption time of
Anticoagulant
Beta blockers
Lidocaine
Quindine
Theophylline
What type of med is it
Histamine ² Antagonist
Acid rebound happens in these types of meds
Calcium Antacids
Potential SE of these drugs is related to acid base balance & electrolytes
They also interfer with the absorption of medication due to changing the pH of the stomach
Antacids
Adverse affects
Gastric rupture
Systemic Alkalosis (headache, nausea, irritation, weakness, tetany)
Hypokalemia
Gastric acid rebound
DIARRHEA & CONSTIPATION
Antacids
Quickest acting PPI
Omeprazole Prilosec