Kach: GI secretions Flashcards
Histamine-2 receptors
When stimulated release hydrochloric acid
Swallowing is controlled by …
The medulla
Vomiting is controlled by…
The CTZ in the medulla
These medications block the release of Hydrochloric acid in response to Gastin
H² Antagonist
Cimetidine
Famotidine
Nizatidine
Ranitinde
Are examples of this medication
With this effect
Histamine ² Antagonist
Block the release of Hydrochloric acid in response to gastrin
____ work to suppress the secretion of Hydrochloric Acid into the Lumen of the stomach
PPI
( - azole)
Sucralfate
GI protectant coat the stomach and prevent further injury from acid
____ inhibit the secretion of gastrin and increase secretion of mucous liming
Prostaglandin
misoprostol
Cimetidine
Famotidine
Nizatidine
Ranitinde
Are examples of…
With what effect
Histamine ² Antagonist
Block release of Hydrochloric acid in response to gastrin
Famotidine (Pepcid AC)
Nizatidine (Axid AR)
Cimetidine (Tagamet HB)
Ranitinde (Zantac)
Are examples of
H² ANTAGONIST
Block release of Hydrochloric acid in response to gastrin
High levels of H² Antagonist can cause
Cardiac arrhythmias
Adverse effects
Diarrhea/ Constipation
Dizzy, headache, confusion, somnolencia, confusion, Hallucinations
Cardiac arrhythmias & Hypotension
Gynecomastia & Impotence
H² Antagonist
Drug interactions
Anticoagulant
Beta blockers
Alcohol
Quinididine, lidocaine, theophylline, chloroquine,
Benzodiazepine
Tri cyclic antidepressants
Nifedipine, pentoxifylline, Procainamide, carbamazepine
H² Antagonist
Used for:
Short term treatment Duodenal or benign gastric ulcers
Treat pathological hypersecretory conditions
Prophylaxis stress induced ulcers
Erosive GERD
Relief symptoms heartburn & acid indigestion
H² Antagonist
(-tidine)
This GI medicine can cause serious electrolyte imbalance in persons with rental impairment
Sodium Bicarbonate