Lipopeptidos Flashcards

1
Q

mencione el unico lipopeptido dado

A

daptomicina

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2
Q

via de adm de la daptomicina

A

ev

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3
Q

via de eliminacion daptomicina

A

renal

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4
Q

mecanismo de accion lipopeptidos

A

inhiben la sintesis de peptidoglucano creando POROS en la pared celular

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5
Q

daptomicina bactericida o bacteriostatico

A

bactericida

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6
Q

gram positivos que cubre daptomicina

A

estreptococo
MRSA
VRE (enterococo resistente a vanco)

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7
Q

que mas cubre la dapto?

A

mas nada, solo gram positivos

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8
Q

efectos adversos daptomicina

A

eleva CPK (debe vigilarse el uso concomitante de estatinas y fibratos), esto puede llevar a insuficiencia renal o fallo renal

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9
Q

categoria en el embarazo daptomicina

A

B

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10
Q

contraindicaciones daptomicina

A

neumonia, porque se inactiva con el surfactante pulmonar

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11
Q

indicaciones daptomicina

A
infecciones severas por cocos gram positivos
IVU por VRE
endocarditis
meningitis
osteomielitis
infecciones piel y tejido blando
fibrosis quistica
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12
Q

atb que da el sindrome del hombre rojo

A

vancomicina

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13
Q

atb que da el sindrome del hombre gris

A

cloranfenicol

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14
Q

atb que da el sindrome de hombre negro

A

tetraciclina

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15
Q

daptomicina tiene mielotoxicidad

A

no

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