Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Biology and Biochem > Lipid synthesis and Storage > Flashcards

Lipid synthesis and Storage Flashcards

You may prefer our related Brainscape-certified flashcards:
AP® Biology flashcards Biology 101 flashcards
1
Q

What lipoprotein is elevated in Type 1 Hypertriglyceridemia

A

Chylomicrons

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Type 1 Hypertriglyceridemia is due to a deficiency in

A

Lipoprotein Lipase (rare)

apoC-2 (rare)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Job of lipoprotein lipase

A

Removes fatty acid from chylomicron and VLDL

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What is the function of apoC-2

A

Activates lipoprotein lipase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Type 1 Hypertriglyceridemia genetics

A

AD

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

VLDL function

A

Transports TG from liver to tissue

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

VLDL apoproteins

A

apoB-100

apoC-2

apoE

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Glycerol 3-P dehydrogenase converts

A

DHAP to Glycerol 3-P

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Type 2a hypercholesterolemia clinical

A
  1. high risk of atherosclerosis and CAD
  2. Xanthomas of the Achilles tendon
  3. Tuberous xanthomas on elbows
  4. Xanthelasmas
  5. Corneal arcus
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

LDL apoproteins

A

apoB-100

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Abetalipoproteinemia is due to deficiency in

A

apoB-100 and apoB-48

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Acetyl CoA carboxylase requires

A

Biotin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What is the primary end product of FA synthesis

A

Palmitic acid (Palmitate)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What lipid is elevated in Type 1 Hypertriglyceridemia

A

Triglycerides

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

FA synthase converts

A

Malonyl CoA to FA palmitate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Function of Chylomicrons

A

Transport dietary TG and cholesterol from intestine to tissue

17
Q

What does LCAT do

A

adds a FA to cholesterol producing Cholesterol esters

18
Q

Type 2a hypercholesterolemia genetic

A

AD

19
Q

Lipid elevated in Type 2a hypercholesterolemia

A

Cholesterol

20
Q

What are the two sources of Glycerol 3-P

A
  1. Reduction of DHAP from glycolysis by glycerol 3-P
  2. Phosphorylation of free glycerol by glycerol kinase
21
Q

Chlyomicron apoproteins

A

apoB-48

apoC-2

apoE

22
Q

Type 1 Hypertriglyceridemia clinical

A

Red-orange eruptive xanthomas

Fatty liver

Acute pancreatitis

Abdominal pain after fatty meal

23
Q

What is needed for the synthesis of Triglycerides

A

Glycerol 3-P

24
Q

LDL function

A

Delivers cholesterol into cell

25
Q

IDL function

A

picks up cholesterol from HDL to become LDL

26
Q

FA synthase requires

A

NADPH

27
Q

Type 2a hypercholesterolemia deficiency in

A

LDL-receptor

28
Q

Lipoprotein elevated in Type 2a hypercholesterolemia

A

LDL

29
Q

Two important essential FA

A

Linolenic acid

Linoleic acid

30
Q

HDL apoprotein

A

apoA-1

31
Q

HDL function

A
  1. Picks up cholesterol accumulating in BV
  2. Delivers cholesterol to liver and steriodogenic tissues via scavenger receptor (SR-B1)
  3. Shuttles apoC-2 and apoE in blood
32
Q

Malic enzyme converts

A

Malate to pyruvate

Increase NADPH

33
Q

LCAT activated by

A

apoA-1

34
Q

What does fatty acyl CoA synthetase do

A

Attach CoA to FA

35
Q

Triglycerides are formed by

A

Attaching 3 FA to Glycerol

36
Q

Acetyl CoA carboxylase converts

A

Acetyl CoA to Malonyl CoA

37
Q

IDL apoproteins

A

apoE

apoB-100

38
Q

Abetalipoproteinemia clinical

A
  1. Steatorrhea
  2. Cerbellar ataxia
  3. Pigmentary degeneration in the retina
  4. Acanthocytes (thorny appearing erythrocytes)
  5. Loss of night vision

Biology and Biochem (15 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions