Lipid pathways Flashcards
Name the pathway
Beta-oxidation
Process 1
- Enzyme
- Reactions
Acyl-CoA dehydrogenase
- FAD → FADH2
Compound A
- Name
- Structure
Fatty acyl-CoA
Compound B
- Name
- Structure
trans-enoyl-CoA
Process 2
- Enzyme
- Reactions
Enoyl-CoA hydratase
- H2O →
Compound C
- Name
- Structure
β-hydroxyacyl-CoA
Process 3
- Enzyme
- Reactions
β-hydroxyacyl-CoA dehydrogenase
- NAD+ → NADH + H+
Compound D
- Name
- Structure
β-ketoacyl CoA
Process 4
- Enzyme
- Reactions
Thiolase
- CoA-SH →
Compound E
- Name
- Structure
Acetyl-CoA
Process 1
- Enzymes
- Reactions
Propionyl-CoA carboxylase
- HCO3- →
- ATP → ADP + P<span>i</span>
Give the structure of Propionyl-CoA
Compound B
- Name
- Structure
D-Methylmalonyl-CoA
Process 2
- Enzyme
- Reactions
Methylmalonyl-CoA epimerase
Compound C
- Name
- Structure
L-Methylmalonyl-CoA
Process 3
- Enzyme
- Reactions
Methyl-malonyl-CoA mutase
With coenzyme B12
Compound D
- Name
- Structure
Succinyl-CoA
Name the pathway
Ketogenesis
Compounds A + B
- Name
- Structure
2 x Acetyl-CoA
Process 1
- Enzyme
- Reactions
Thiolase
- → Acetoacetyl-CoA
Compound C
- Name
- Structure
Acetoacetyl-CoA
Process 2
- Enzyme
- Reactions
HMG-CoA synthase
- Acetyl-CoA → CoA-SH
Compound D
- Name
- Structure
HMG-CoA
Process 3
- Enzyme
- Reactions
HMG-CoA lyase
- → CoA-SH
Compound E
- Name
- Structure
Acetoacetate
Process 4
- Enzyme
- Reactions
Non-enzymatic decarboxylation
- → CO2
Compound F
- Name
- Structure
Acetone
Process 5
- Enzyme
- Reactions
D-β-hydroxybutyrate dehydrogenase
- NADH + H+
Compound G
- Name
- Structure
D-β-hydroxybutyrate
Compound A
- Name
- Structure
D-β-hydroxybutyrate
Process 1
- Enzyme
- Reactions
D-β-hydroxybutyrate dehydrogenase
- NAD+ → NADH
Compound B
- Name
- Structure
Acetoacetate
Process 2
- Enzyme
- Reactions
SCOT
- Succinyl-CoA → Succinate
Compound C
- Name
- Structure
Acetoacetyl-CoA
Process 3
- Enzyme
- Reactions
β-ketothiolase
- CoA-SH →
Compound D
- Name
- Structure
Acetyl-CoA
Process 4
- Enzyme
- Reactions
Citrate Synthase
Name the pathway
Fatty acid synthesis
Compound A (A)
- Name
- Structure
Acetyl-ACP
Compound B (M)
- Name
- Structure
Malonyl-ACP
Process 1
- Enzyme
- Reactions
- Condensation*
- → ACP + CO2
Compound C
- Name
- Structure
β-ketoacyl-ACP
Process 2
- Enzyme
- Reactions
Keto group reduction
- NADPH → NADP+
Compound D
- Name
- Structure
β-hydroxyacyl-ACP
Process 3
- Enzyme
- Reactions
- Dehydration*
- → H2O
Compound E
- Name
- Structure
trans-2-enoyl-ACP
Process 4
- Enzyme
- Reactions
- Enoyl reduction*
- NADPH → NADP+
Compound F
- Name
- Structure
Acyl-ACP
Compound A
- Name
- Structure
Glycerol-3-phosphate
Process 1
- Enzyme
- Reactions
GPAT
- FA-CoA → CoA-SH
Compound B
- Name
- Structure
Monoacylglycerol-P
Name the pathway
Fat (TAG) synthesis
Process 2
- Enzyme
- Reactions
AGPAT
- FA-CoA → CoA-SH
Compound C
- Name
- Structure
Phosphatidic acid
Process 3
- Enzyme
- Reactions
PAP
- H2O → Pi
Compound D
- Name
- Structure
Diacylglycerol
Process 4
- Enzyme
- Reactions
DGAT
- FA-CoA → CoA-SH
Compound E
- Name
- Structure
Triacylglycerol
