Lipid pathways Flashcards

1
Q

Name the pathway

A

Beta-oxidation

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2
Q

Process 1

  • Enzyme
  • Reactions
A

Acyl-CoA dehydrogenase

  • FAD → FADH2
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3
Q

Compound A

  • Name
  • Structure
A

Fatty acyl-CoA

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4
Q

Compound B

  • Name
  • Structure
A

trans-enoyl-CoA

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5
Q

Process 2

  • Enzyme
  • Reactions
A

Enoyl-CoA hydratase

  • H2O →
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6
Q

Compound C

  • Name
  • Structure
A

β-hydroxyacyl-CoA

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7
Q

Process 3

  • Enzyme
  • Reactions
A

β-hydroxyacyl-CoA dehydrogenase

  • NAD+ → NADH + H+
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8
Q

Compound D

  • Name
  • Structure
A

β-ketoacyl CoA

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9
Q

Process 4

  • Enzyme
  • Reactions
A

Thiolase

  • CoA-SH →
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10
Q

Compound E

  • Name
  • Structure
A

Acetyl-CoA

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11
Q

Process 1

  • Enzymes
  • Reactions
A

Propionyl-CoA carboxylase

  • HCO3-
  • ATP → ADP + P<span>i</span>
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12
Q

Give the structure of Propionyl-CoA

A
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13
Q

Compound B

  • Name
  • Structure
A

D-Methylmalonyl-CoA

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14
Q

Process 2

  • Enzyme
  • Reactions
A

Methylmalonyl-CoA epimerase

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15
Q

Compound C

  • Name
  • Structure
A

L-Methylmalonyl-CoA

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16
Q

Process 3

  • Enzyme
  • Reactions
A

Methyl-malonyl-CoA mutase

With coenzyme B12

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17
Q

Compound D

  • Name
  • Structure
A

Succinyl-CoA

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18
Q

Name the pathway

A

Ketogenesis

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19
Q

Compounds A + B

  • Name
  • Structure
A

2 x Acetyl-CoA

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20
Q

Process 1

  • Enzyme
  • Reactions
A

Thiolase

  • → Acetoacetyl-CoA
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21
Q

Compound C

  • Name
  • Structure
A

Acetoacetyl-CoA

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22
Q

Process 2

  • Enzyme
  • Reactions
A

HMG-CoA synthase

  • Acetyl-CoA → CoA-SH
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23
Q

Compound D

  • Name
  • Structure
A

HMG-CoA

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24
Q

Process 3

  • Enzyme
  • Reactions
A

HMG-CoA lyase

  • → CoA-SH
25
Q

Compound E

  • Name
  • Structure
A

Acetoacetate

26
Q

Process 4

  • Enzyme
  • Reactions
A

Non-enzymatic decarboxylation

  • → CO2
27
Q

Compound F

  • Name
  • Structure
A

Acetone

28
Q

Process 5

  • Enzyme
  • Reactions
A

D-β-hydroxybutyrate dehydrogenase

  • NADH + H+
29
Q

Compound G

  • Name
  • Structure
A

D-β-hydroxybutyrate

30
Q

Compound A

  • Name
  • Structure
A

D-β-hydroxybutyrate

31
Q

Process 1

  • Enzyme
  • Reactions
A

D-β-hydroxybutyrate dehydrogenase

  • NAD+ → NADH
32
Q

Compound B

  • Name
  • Structure
A

Acetoacetate

33
Q

Process 2

  • Enzyme
  • Reactions
A

SCOT

  • Succinyl-CoA → Succinate
34
Q

Compound C

  • Name
  • Structure
A

Acetoacetyl-CoA

35
Q

Process 3

  • Enzyme
  • Reactions
A

β-ketothiolase

  • CoA-SH →
36
Q

Compound D

  • Name
  • Structure
A

Acetyl-CoA

37
Q

Process 4

  • Enzyme
  • Reactions
A

Citrate Synthase

38
Q

Name the pathway

A

Fatty acid synthesis

39
Q

Compound A (A)

  • Name
  • Structure
A

Acetyl-ACP

40
Q

Compound B (M)

  • Name
  • Structure
A

Malonyl-ACP

41
Q

Process 1

  • Enzyme
  • Reactions
A
  • Condensation*
  • → ACP + CO2
42
Q

Compound C

  • Name
  • Structure
A

β-ketoacyl-ACP

43
Q

Process 2

  • Enzyme
  • Reactions
A

Keto group reduction

  • NADPH → NADP+
44
Q

Compound D

  • Name
  • Structure
A

β-hydroxyacyl-ACP

45
Q

Process 3

  • Enzyme
  • Reactions
A
  • Dehydration*
  • → H2O
46
Q

Compound E

  • Name
  • Structure
A

trans-2-enoyl-ACP

47
Q

Process 4

  • Enzyme
  • Reactions
A
  • Enoyl reduction*
  • NADPH → NADP+
48
Q

Compound F

  • Name
  • Structure
A

Acyl-ACP

49
Q

Compound A

  • Name
  • Structure
A

Glycerol-3-phosphate

50
Q

Process 1

  • Enzyme
  • Reactions
A

GPAT

  • FA-CoA → CoA-SH
51
Q

Compound B

  • Name
  • Structure
A

Monoacylglycerol-P

52
Q

Name the pathway

A

Fat (TAG) synthesis

53
Q

Process 2

  • Enzyme
  • Reactions
A

AGPAT

  • FA-CoA → CoA-SH
54
Q

Compound C

  • Name
  • Structure
A

Phosphatidic acid

55
Q

Process 3

  • Enzyme
  • Reactions
A

PAP

  • H2O → Pi
56
Q

Compound D

  • Name
  • Structure
A

Diacylglycerol

57
Q

Process 4

  • Enzyme
  • Reactions
A

DGAT

  • FA-CoA → CoA-SH
58
Q

Compound E

  • Name
  • Structure
A

Triacylglycerol