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Biochem block 3 > Lipid 2 > Flashcards

Lipid 2 Flashcards

1
Q

2.1

A

ankrin

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2
Q

1

A

spectrin

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3
Q

band 3

A

pump ass with anion transport(integral protein)

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4
Q

glycophorin

A

antigenic determinant of rbc

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5
Q

glycophorin

A

b/n 3 and 4.1

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6
Q

peripheal ext. proteins

A

1,2.1,2.2, actin

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7
Q

band 7

A

G3P hydrogenase

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8
Q

which band is inovlved in glycolysis

A

band 7

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9
Q

abundant antigen

A

glycophorin

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10
Q

100 sugars – organized in – polysaccharide chains

A

100 sugars – organized in 16 polysaccharide chains in glycophorin

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11
Q

carb sugar chain

A

on ext domain of glycophorin (70aa)

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12
Q

rich in charge

A

internal domain of Glycophorin

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13
Q

apolar hydrophobic AA

A

trans bilayer of glycophorin

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14
Q

rise residue of alpha helix

A

1.5 ang

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15
Q

35 ang

A

trans bilayer of glycophorin

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16
Q

greater temp

A

greater % uniform fluor cells(proteins)

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17
Q

TG

A

broken down into FA for cell uptake

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18
Q

once in cell

A

FA converts to TG or used for NRG

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19
Q

cholesterol made in liver and

A

converted to CE

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20
Q

apoliporproteins

A

A,B,C,E

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21
Q

apoliporproteins and lipids

A

plasma lipoproteins

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22
Q

Low density lipoproteins (LDL) –

A

bad cholesterol

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23
Q

High density lipoproteins (HDL

A

good cholesterol

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24
Q

exogenous fat delivery

A

CM

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25
Q

VLDL

A

– endogenous fat delivery

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26
Q

LDL –

A

cholesterol delivery system

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27
Q

HDL

A

– cholesterol removal from cells

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28
Q

high density correlates with artherosclerosis

A

Ldl

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29
Q

STAtin

A

lower LDL higher HDL

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30
Q

tf cells can directly take up TG

A

F only take FA

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31
Q

OH group on cholesterol

A

makes ester bond with ester

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32
Q

lipid dec. and protein inc

A

as you go from CM to VLDL to LDL to HDL

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33
Q

has apo BCE

A

CM and VLDL

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34
Q

only apo B

A

LDL

35
Q

apo ACE

A

HDL

36
Q

as you go from CM to VLDL to LDL to HDL

A

size decreases

37
Q

prigin in liver

A

VLDL and HDL

38
Q

intestine origin

A

CM

39
Q

VLDL catabolism origin

A

LDL

40
Q

catabolized in adipose tissue

A

CM and VLDL

41
Q

catabolized in Liver

A

LDL and HDL

42
Q

catabolized in liver and all periphereal cells

A

LDL

43
Q

carry TG

A

CM and VLDL

44
Q

CE carried by

A

LDL

45
Q

CE and phospholipids

A

carried by hdl

46
Q

how to get rid of cholesterol

A

—>liver–> bile salts—> SI—> secreted in feces

47
Q

– plasma enzyme (in the bloodstream)

A

LPL

48
Q

breaks down TG→FA

A

LPL

49
Q

activated as cofactor APO-C (CM and VLDL)

A

LPL

50
Q

Lecithin cholesterol acyl transferase (LCAT

A

acyl chains on lecithin and transfers to cholesterol to make a CE

51
Q

– activated by cofactor APO-A (HDL)

A

Lecithin cholesterol acyl transferase (LCAT

52
Q

activated by cofactor APO-A (HDL) in the bloodstream

A

LCAT

53
Q

takes acyl Co-A and cholesterol inside of liver cells

A

ACAT

54
Q

in liver cell

A

ACAT

55
Q

HMG Co-A Reductase

A

makes cholesterol the rate limiting step of cholesterol biosynthesis

56
Q

Intracellular enzymes

A

HMG Co-A Reductase ACAT

57
Q

in blood stream

A

LDL

58
Q

LPL cofactor

A

apo C

59
Q

APO-B –

A

ligand for LDL receptor

60
Q

APO-A –

A

LCAT cofactor

61
Q

APO-A –

A

ligand for 2 receptors/transporters ABCA1&SRB1

62
Q

lipoprotein

A

phospholipid with apoprotein croplet containing TG and CE

63
Q

apo protein

A

stabilize droplet and have act enzyme and transporters

64
Q

chylomicron

A

made from interstinal mucosal cell

65
Q

ACAT

A

Chol-> CE in int. mucosal cell

66
Q

apo protein C and E

A

CM

67
Q

LPL

A

TG to FA in CM and transfers to adipose cels

68
Q

once in Adipose cell

A

FA made back to TG

69
Q

after CM delivers TG to adipose cell

A

it delivers CE to Liver

70
Q

CM binds to liver thru

A

APo E

71
Q

Liver make

A

TG from F CE FROM CHOL bile from Chol

72
Q

VLDL

A

come from Liver

73
Q

VLDL

A

apo B and C TG and CE

74
Q

go to adipose tissues

A

LDL and VLDL

75
Q

LPL acts in

A

LDL and VLDL to make FA and deliver to adipose tissue

76
Q

after coming from adipose tissue

A

LDL is formed from VLDL

77
Q

only hase apo B

A

LDL after adipose tissue

78
Q

endocytosis

A

of LDL particle on Peripheal cell(CE in)

79
Q

adrenal gland recieves

A

LDL and takes in CE to form Chol(make steroid hormones)

80
Q

tf all cells have ability to make cholesterol

A

T but only liver and adrenal cells do

81
Q

Liver secretes APO a

A

to another peripheal cell

82
Q

ABCA1

A

transporter for APO A

83
Q

Chol and phospholipid combined

A

with APO A1 to make HDL

84
Q

SBR1

A

on liver and recieves HDL(with chol and phospholipid)

Biochem block 3 (12 decks)

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