Lily M Flashcards
1
Q
Notch Signaling is a complex pathway that increases after spinal injury, which causes progenitor cells to proliferate.
A
False
2
Q
DAPT is a drug they used in the experiment that specifically inhibits gamma-secretase, preventing activation of the Notch response
A
True
3
Q
What is PCNA cells?
A
Proliferating Cell Nuclear Antigen; Antigen expressed in the nuclei of cells during DNA synthesis phase
4
Q
Because Notch Signaling is so complex, it’s receptors and it’s proposed ligands can govern…
A
Differentiation, Proliferation, Apoptosis
5
Q
What was the result found on the DAPT treatment and did it improve the swimming performance of the zebrafish?
A
- The results found in the DAPT treatment showed increased numbers of motor neurons, but no significant improvement in the swimming performance of fish from the spinal lesion occurred.
