Katie Benthall

Question 1

Propriospinal neurons can project ipsilaterally or contralaterally.

Answer 1

T

Question 2

Propriospinal neurons are thought to form a/an ______ pathway for the locomotor signal to travel from the brainstem to CPGs.

Answer 2

Indirect

Question 3

Why have the authors proposed that propriospinal neurons be investigated as a potential spinal cord injury therapy?

Answer 3

c) Axons regenerated across the injury could synapse on propriospinal neurons, and the propriospinal pathway could relay the locomotor signal to CPGs in lower levels of the spinal cord.

Question 4

The authors conclude that indirect propriospinal pathways are insufficient conduits for the descending activation of spinal locomotor networks in the neonatal rat. __

Answer 4

False

Question 5

Why did the authors use brainstem-spinal cord preparations with staggered contralateral hemisections to investigate their research question?

Answer 5

The staggered contralateral hemisections interrupted long, direct bulbospinal pathways and left some propriospinal pathways intact. Thus, any locomotor-like activity recorded from lumbar ventral roots could be attributed solely to propriospinal transmission.