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NMSK A Test 2 > LG4.3 Arthritis II – Winfield > Flashcards

LG4.3 Arthritis II – Winfield Flashcards

1
Q

What are general characteristics of reactive arthritis?

A

-Acute, polyarticular

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2
Q

What are the symptoms of reactive arthritis?

A
  • Rash on hands, feet, penis.

- Urethritis, Iritis

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3
Q

What is the classic triad of reactive arthritis?

A

Arthritis, conjunctivitis, urethritis

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4
Q

What are the general symptoms of ankylosing spondylitis?

A
  • persistent low back pain in teenager or early 20’s

- Spinal fusion with stooped posture and loss of spinal mobility

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5
Q

Define spondylitis?

A

A painful condition of the spine resulting from the degeneration of the intervertebral disks.

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6
Q

What are the main characteristics of ankylosing spondylitis?

A
  • More males
  • In lumbar spine, hips, pelvis, eye
  • Seronegitive spondyloarthropathies
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7
Q

What are the main genetic predisposition of ankylosing spondylitis?

A

Class 1: HLA-B27

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8
Q

What are the general characteristics of Enteropathic arthritis?

A
  • 20% of IBD develop a peripheral arthritis
  • course of arthritis often fluctuates with the activity of the underlying bowel involvement.
  • 10-20% spinal involvement
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9
Q

What are extra-articular manifestations of enteropathic arthritis?

A

Inflammatory eye disease and cutaneous lesions

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10
Q

What is the problem in psoriasis?

A
  • The skin grows to quickly forming skin lesions.
  • Nail discolorations and pitting
  • can develop arthritis
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11
Q

What is the cause of psoriasis?

A

T-cell mediated disease with a genetic basis

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12
Q

Who gets psoriasis?

A
  • Males=females

- Caucasians

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13
Q

What is the general characteristics of Psoriatic arthritis?

A
  • Skin lesions and nail discoloration

- caused by psoriasis

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14
Q

What does it mean for a diseases to be Seronegitive spondyloarthropathies?

A
  • No RF and ACPA values

- increased HLA-B27

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15
Q

What is Inflammatory bowel disease?

A

Diseases that cause chronic recurrent inflammation of the intestines

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16
Q

What are the causes of inflammatory bowel disease?

A
  • Genetic family risk
  • Caucasians have higher risk
  • Jew have higher risk
  • Ages 10-30 and 50-60
17
Q

What are the symptoms of inflammatory bowel disease?

A

Abdominal cramps and pain, diarrhea, weight loss, and hematochezia

18
Q

What are the clinical presentation of Rheumatoid Arthritis?

A
  • Joint tenderness and swelling
  • Morning joint stiffness for an hour or more
  • Progressive joint destruction
19
Q

What are extra-articular manifestations of Rheumatoid Arthritis?

A

-Scleritis, pericarditis, conduction defects, lung nodules, pulmonary fibrosis, gastritis, peptic ulcer disease 2nd to NSAIDS.

20
Q

What is the cause of Rheumatoid Arthritis?

A
  • Unknown
  • Possible infectious agent
  • Genetic factors
21
Q

What are risk factors of Rheumatoid Arthritis?

A
  • Female 3:1 male
  • Smoking
  • onset at any age, most common 40-50
22
Q

What are lab test for Rheumatoid Arthritis?

A
  • RF
  • Anti-cyclic cirtullinated peptide(ACCP)
  • Increased ESR
  • Increased CRP
23
Q

What are the non-pharmacologic treatments for Rheumatoid Arthritis?

A
  • Heat

- Range of motion exercises

24
Q

What are pharmacologic treatments for Rheumatoid Arthritis?

A
  • NSAIDS
  • Corticosteroids
  • Disease Modifying Antirheumatic Drugs (DMARD)
  • Oral Hydroxychloroquine, Sulfasalazine, and Methotrexate
25
Q

What are the clinical presentation of erosive inflammatory osteoarthritis?

A
  • Typical OA has enlargement of bones over the distal and proximal finger joints.
  • Swelling of the soft tissue in the proximal and distal interphalangeal joints.
26
Q

What are common labs for erosive inflammatory osteoarthritis?

A
  • RF/ACCP are negative

- ESR and CRP increased

27
Q

What are the treatments of erosive inflammatory osteoarthritis?

A
  • ROM exercises

- PRN pain meds and no steroidal anti-inflammatory drugs for symptom relief

28
Q

What are main lab values for septic arthritis?

A

-Lab: Synovial WBC >100,000 PMNs are 90% or above

29
Q

What are main causes of septic arthritis?

A
  • Mycrobacterium SPP
  • Fungal infections
  • Viral infections

NMSK A Test 2 (27 decks)

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