LG3.6 Microbiology of Joint Infections – Dr. Pettit Flashcards
What type of hemolysis does S. aureus cause?
Beta
Is S. aureus gram +/-?
positve
What is the catalase, coagulase, and fermenter type of S. aureus?
Catalase positive, coagulase positive, and it is a mannitol fermentor
What are the main virulence factors of S. aureus?
- Protein A: Binds to Fc region of IgG
- Fibronectin-binding protein
- Cytolytic Exotoxins: PVL
What type of hemolysis does S. epidermis have?
Gamma hemolysis
What is the catalase, coagulase, and fermenter type of S. epidermis?
Catalase positive, coagulase negative, and mannitol fermentor negative
What are the main virulence factors of S. epidermis
- Slime layer (attachement to tissues/prosthetics)
- Adhesins (collagen, fibrinogen, elastin)
- Lipases, proteases
- Biofilms
What is the gram stain and shape of Kingella kingae?
Gram negitive and coccobacillus
Where is Kingella kingae normal microbiota?
oropharynx
What type of oxygen use does Kingella kingae have?
Facultative anaerobe
What type of hemolysis does Kingella kingae cause?
Beta hemolytic
Is Kingella kingae oxidase positive or negative?
Positive
What is a leading cause of septic arthritis?
Kingella kingae
What are the virulence factors of Kingella kingae?
- Pili
- Beta-hemolysin: lysis epithelial cells, synovial cells, macrophages
What is the Gram stain and shape of Neisseria gonorrhoeae?
Small Gram Negative diplococcus