Lesson 8 Flashcards

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1
Q

Не все гены устойчивости известны

A

incomplete knowledge of the genetic basis of resistance

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2
Q

Не генетические методы аст основные в клинических лабораториях

A

Culture-based antimicrobial susceptibility testing (AST) is still the primary method employed by clinical laboratories

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3
Q

Культуральнвеиметолытнпимоделируют то что происходит в организме человека

A

Culture-based AST measures resistance in a highly constrained setting that does not reflect the variance of expression of the phenotype, especially during human infections

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4
Q

Наш метод выявляет персистеров которых не ловят обычные аст и вызывают персистируюзую инфекцию

A

persisters (106), which are not detected by AST, can survive treatment and cause recurrent infections

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5
Q

Все это приводит к неэффективности аст

A

This underlies the fundamental issue of using MIC breakpoints to define resistance.

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6
Q

Сложно культивируемые патогены

A

hard-to-grow species

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7
Q

В целом

A

Quite frankly

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8
Q

Мысли шире

A

Think outside the box

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9
Q

Спустя 6 месяцев

A

Fast forward 6 months

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10
Q

Извините, если я говорю только через узкую призму своих знаний

A

Sorry if I’m speaking through my lands

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11
Q

Перенесённый на самолете/эвакуация

A

Airlifted

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12
Q

Я отвлёкся

A

I just slipped my mind

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13
Q

Могли быть спасены/могли не умереть

A

Died unnecessary

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14
Q

Смертники

A

Suicide bomber

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15
Q

Смотрю с точки зрения микробиома.

A

Looking from Microbiome land

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16
Q

Необходимо

A

Vital unmet need

17
Q

Лечение пациентов после тяжелых случаев

A

Post acute care facilities

18
Q

Избежать лишних АБ

A

Avoid overuse of ab

19
Q

Лечение пациентов после тяжелых случаев

A

Post acute care facilities

20
Q

Избежать лишних АБ

A

Avoid overuse of ab