Lesson 3: Extensions of Mendelian Inheritance

Question 1

inheritance of a trait that is determined by a gene located on one of the sex chromosomes (X and Y)

Answer 1

sex-linked inheritance

Question 2

traits controlled by genes present on X chromosomes

Answer 2

X linked inheritance

Question 3

Present in both males and females

Answer 3

X linked inheritance

Question 4

May be in dominant or recessive

Answer 4

X linked inheritance

Question 5

daughters of an affected father but none of his sons are affected

Answer 5

X linked inheritance

Question 6

__ are expressed in males and homozygous female

Answer 6

Recessive X linked traits

Question 7

No dominant and recessive

Answer 7

Y linked inheritance

Question 8

traits controlled by genes present on Y chromosome

Answer 8

Y linked inheritance

Question 9

present in males only

Answer 9

Y linked inheritance

Question 10

all sons of an infected father are affected by __

Answer 10

Y linked traits: Y linked inheritance

Question 11

Red-green colorblindness and hemophilia A

Answer 11

X linked inheritance

Question 12

Maleness and hairy ears

Answer 12

Y linked inheritance

Question 13

Generally, it manifests only in males. Usual transmission is from mother to son

Answer 13

X-linked Recessive Inheritance

Question 14

recessive X linked inheritance
- A male with an affected allele on his single X chromosome is __ and cannot transmit the disorder to __ offspring.
- All his daughters would be __

Answer 14

• hemizygous
• male
• obligate carriers

Question 15

• inherited as an X-linked recessive genetic disorder that, with rare female exceptions, most often affects males.
• inborn error metabolism purine
• deficiency of enzyme
• excessive uric acid in blood

Answer 15

Lesch-Nyhan Syndrome (X linked recessive inheritance)

Question 16

hen a person who is genetically male (who has one X and one Y chromosome) is resistant to male hormones (called androgens). As a result, the person has some of the physical traits of a woman, but the genetic makeup of a man.

Answer 16

Androgen insensitivity syndrome (AIS)
(X linked recessive inheritance)

Question 17

• more common in males than in females
• all daughters of an affected father but none of his sons are affected
• any heterozygous mother will pass the trait equally to half her sons and half of her daughters

Answer 17

X-linked dominant inheritance

Question 18

a disorder of bone mineralization caused due to defects (inherited/acquired) in the renal handling of phosphorus.

Answer 18

Hypophosphatemic rickets (X linked dominant inheritance)

Question 19

Y-linked Genes( Holandric genes) – in males only (3)

Answer 19

1) porcupine man-skin
2) Webbed toes
3) hypertrichosis

Question 20

covered with scales; in England (1716); appeared in all six sons but not in daughters

Answer 20

porcupine man-skin (Holandric genes)

Question 21

web-like connection between 2nd and 3rd toes

Answer 21

webbed toes (holandric genes)

Question 22

excessive hair development in the outer rim of ears

Answer 22

hypertrichosis (holandric genes)

Question 23

*In moths and chicken
*Males are __, females are __

Answer 23

Z-Linked Inheritance
- homogametic
- heterogametic