Lesson 12 - Exam 2

Question 1

Forms of inflammation:

Answer 1

1. Serous.
2. Fibrinous.
3. Purulent.
4. Ulcerative.

Question 2

Serous inflammation:

Answer 2

1. AKA serousoitis.
2. Forms a serous exudate, mostly made of albumin and Ig that leaked from vessels.
3. Seen in viral infections.

Question 3

Fibrinous inflammation:

Answer 3

1. Forms a fibrinous exudate - due to bacterial infections.
2. Associated with strep throat.
3. Indication of more severe inflammation.

Question 4

Purulent inflammation:

Answer 4

1. Pus from dead PMN’s or tissue debris.
2. Caused by pus-forming bacteria, like strep or staph.

Question 5

Ulcerative inflammation:

Answer 5

1. circumscribed inflammatory and often suppurating (pus forming) lesion.
2. Often found on the skin or internal mucous surface.
3. Results in necrosis of tissue.

Question 6

An abscess where the accumulation of pus occurs in the preformed cavity is called -

Answer 6

Empydema.

Question 7

True or false: Older abscesses are surrounded by adipose tissue.

Answer 7

FALSE - older abscesses are surrounded by granulation tissue that was vascularized connective tissue.

Question 8

__________ are rich in angioblasts, fibroblasts, myofibroblasts, and macrophages.

Answer 8

Abscesses.

Question 9

Define a granuloma:

Answer 9

A granuloma is a mass of chronic immune cells, composed of epitheloid cells, lymphocytes, macrophages, and multi-nucleated giant cells.

Question 10

Granulomatous disease is caused by:

Answer 10

A defect in phagocytosis, leading to build up of granulomas.

Question 11

Chronic granulomatous disease - X-linked vs autosomal recessive rates:

Answer 11

1. 65% of cases are X-linked recessive.
2. 35% of cases are autosomal recessive.

Question 12

Mechanism of chronic granulomatous disease:

Answer 12

1. Mutations in the NADPH oxidase system, causes dysfunction in phagocytosis, which decreases the cells ability to destroy offending microbes.
2. Macrophages will fuse together to form multinucleated giant cells.

Question 13

Sarcoidosis:

Answer 13

1. Idiopathic inflammatory disease that is charecterized by the formation of discrete granulomas.
2. Lung is almost always involved.
3. Causes sarcoid myocarditis.
4. Workers exposed to particles in the air are at higher risk.
5. Not associated with necrosis.