Lecture: Renal Diseases Flashcards
Decomposition of immune complexes, formed in conjunction with group A streptococcus infection on the glomerular membranes
Acute Glomerulonephritis
Deposition of immune complexes from systemic immune disorders on the glomerular membrane
Rapidly-progressive Glomerulonephritis
Attachment of cytotoxic antibody formed during viral respiratory infections to glomerular and alveolar basement membranes
Goodpasture’s Syndrome
Anti-neutrophilic cytoplasmic autoantibody binds to neutrophils in vascular walls producing damage to small vessels in the lungs and glomerulus
Wegener’s Granulomatosis
Occurs primarily in children following viral respiratory infections; a decrease in platelets disrupts vascular integrity
Henoch-Schoenlein purpura
Deposition of IgA on the glomerular membrane resulting from increased levels of serum IgA
IgA nephropathy (Berger’s disease)
Thickening of the glomerular membrane following IgG immune complex deposition associated with systemic disorders
Membranous glomerulonephritis
Cellular proliferation affects the capillary walls or the glomerular basement membranes, possibly immune-mediated
Membranoproliferative glomerulonephritis
A marked decrease in renal function resulting from glomerular damage precipitated by other renal disorders
Chronic glomerulonephritis
Disruption of the electrical charges that produce the tightly-fitting podocyte barrier results in a massive loss of protein and lipids
Nephrotic syndrome
Disruption of podocytes occurs primarily in children following allergic reactions and immunizations
Minimal change diseases (Lipid nephrosis)
Disruption of podocytes in certain areas of glomeruli associated with heroin and analgesic abuse and acquired immunodeficiency syndrome
Focal-segmented glomerulosclerosis
This type of glomerulonephritis has the presence of RBC casts, granular casts and dysmorphic RBC
Acute glomerulonephritis
The anti-glomerular basement membrane antibody test is used on what glomerular disorder?
Goodpasture’s syndrome
The anti-neutrophilic cytoplasmic antibody (ANCA) is used on what glomerular disorder?
Wegener’s granulomatosis
Stool occult blood can be used to detect what glomerular disorder?
Henoch-Schoenlein purpura
Anti-nuclear antibody, hepatitis B surface antigen and FTA-ABS can be used to detect what glomerular disorder?
Membranous glomerulonephritis
FTA-ABS means?
Fluorescent Treponemal Antibody-Absorption Test
Chronic glomerulonephritis and nephrotic syndrome can be detected by what tests?
Blood urea nitrogen
Serum Creatinine
Creatinine Clearance
Electrolytes
Glucosuria, cellular and granular casts, and waxy and broad casts are present in what glomerular disorder?
Chronic glomerulonephritis
Oval fat bodies, renal tubular cells, fat droplets and fatty and waxy casts are present in what glomerular disorder?
Nephrotic syndrome
Damage to the renal tubular cells is caused by ischemia or toxic agents
Acute tubular necrosis