Lecture: Intro Flashcards

1
Q

Approach to clinical cases

A
  • Signalment
  • History: Take good notes
  • Physical examination
  • List of problems and differential diagnoses
  • Diagnostic tests
  • Therapy
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2
Q

History

A
  • Onset
  • Length of time of disease
  • Seasonality
  • Relatives
  • Zoonosis
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3
Q

History of Medications

A
  • Antibiotics?
    • dose
    • duration
    • response
    • alone or with glucocorticoids
  • flea control
  • topical therapy
  • special diet
  • supplements
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4
Q

Physical exam

A
  • look for primary lesions
  • may need to clip area
  • Prurities (on a scale of 1-10)
  • Look for fleas, flea dirt
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5
Q

Primary lesions

A
  • Macule
  • Papule
  • Plaque
  • Pustule
  • Vesicle
  • Bulla
  • Nodule
  • Wheal
  • Tumor
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6
Q

Macule

A
  • altered skin color, no elevation
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7
Q
A

Macules

Can be dark spots as well

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8
Q

Papule

A
  • Solid raised lesion
  • distinct borders
  • less than 1 cm in diameter
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9
Q
A
  • Papule
  • raised and itchy
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10
Q

Plaque

A
  • Elevated lesion with a flattened top greater than 10mm in size
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11
Q
A
  • Plaque
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12
Q

Pustule

A
  • Elevations villed with pus
  • common in
    • bacterial infections
    • inflammatory skin diseases
  • Follicular vs non follicular
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13
Q

DDX for papular/pustular eruption

Follicular

A
  • Demodex
  • Dermatophytes
  • Bacterial: Staphylococcus
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14
Q

DDX for papular/pustular eruption

Non follicular

A
  • Flea
  • Food
  • Contact
  • Scabies
  • Drug eruption
  • Dermatomyositis
  • Sterile pustular diseases
  • Autoimmune
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15
Q
A

Papular/pustular eruption

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16
Q

Vesicle

A
  • Small, clear fluid-filled blister
    • less than 1 mm in diameter
    • possible causes
      • acute contact dermatitis
      • some autoimmune skin diseases
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17
Q
18
Q

Bulla

A
  • Clear fluid-filled blister > 10mm in diameter
  • common causes
    • burns
    • contact dermatitis
    • drug reactions
    • autoimmune diseases
19
Q

Nodule

A
  • Firm lesions that extend into the dermis or subcutaneous tissue
20
Q
21
Q

Tumor

A
  • Swelling or enlargement
  • Usually, not always neoplastic
22
Q
23
Q

Wheal (Hive)

A
  • Sharply circumscribed skin elevation from superficial dermis edema
  • typical of allergic reactions
  • illustrates diascopy: lesion disappears when you press on it
24
Q

Secondary lesions

A
  • epidermal collarettes
  • scale
  • crust
  • scar
  • ulcer
  • excoriation
  • lichenification
  • hyperpigmentation
  • hyperkeratosis
25
Epidermal collarettes
* Secondary lesions developed from previous pustules
26
Epidermal collarette
27
Scale
* Flake of abnormal or compacted epithelial cells
28
Crust
* Dried exudate (scab) * leukocytes * bacteria (common)
29
Scar
* Fibrotic area resulting from healing of a wound or lesion (deep to dermis, I think) * Typically associated with * alopecia * depigmentation * thinner dermis
30
Ulcer
* Loss of substance on a cutaneous surface exposing inner layers or tissues * May imply full thickness loss of epidermis
31
* ulcer
32
Excoriations
* Superficial erosion (doesn't get deep to dermis) * usually implies scratching or abrasion
33
Lichenification
* Thickening of skin * secondary to trauma/inflammation * indicated chronicity * can be accompanied by hyperpigmentation
34
Lichenification
35
Hyperpigmentation
* Increased pigmentation * commonly associated wtih lichenification
36
Hyperkeratosis
* Thickening of stratum corneum due to increased number of keratinized cells * Typically occurs in footpads
37
Depigmentation
* Loss of pigmentation * typical of inflammatory/neoplastic processes affecting the basement membrane
38
Salivary staining
39
Skin scraping
* Superficial * Deep
40
Direct microscopic exam
* Useful to detect arthrospores
41
Cytology
* Useful to dx secondary infections * skin * tape * swab * ear * swab * Fine needle aspirates of masses
42
Malassezia does not respond to
steroids