Lecture 7 - Motor Units And Movement Flashcards
What does the somatic system consist of
Skeletal muscle and all the elements of the nervous system that controls them
What comprises the neural elements of the motor system
Upper motor neurones and lower motor neurones
Where are upper motor neurones found
In the brain
Where are lower motor neurones found
Their soma is in the brain stem and the cell bodies are in the ventral horn of the spinal cord
Function of upper motor neurones
Supply output to lower motor neurones and modulate their activity
Other than upper motor neurones, where else do lower motor neurones receive input from
Proprioceptors and interneurones
Function of LMNs
Command muscle contraction and form the final common pathway
What are LMNs comprised of
Alpha motor neurones
Function of the alpha motor neurones in LMNs
Innervate the bulk of fibres within a muscle that generate force
What do gamma motor neurones innervate
The muscle spindle
Where do axons of LMNs exit the spinal cord
In ventral roots
What do the ventral roots join with
Dorsal roots
What do joined ventral and dorsal roots form
A mixed spinal nerve
What is contained within a mixed spinal nerve
Sensory and motor fibres
Where do motor units belong
To a spinal segment
What are the spinal segments
Cervical (C1-8)
Thoracic (T1-12)
Lumbar (L1-5)
Sacral (S1-5)
Are motor neurones equally distributed through the spinal cord
Nope
What areas of the spinal cord are the most motor neurones found
The cervical enlargement (C3-T1) and the lumbar enlargement (L1-3)
What does the cervical enlargement supply
The upper limb
What does the lumbar enlargement supply
The lower limb
Motor neurones that innervate distal and proximal musculature are mainly found
In the lumbar-sacral segment
Motor neurones that innervate axial musculature are found
At all levels of the spinal cord
An alpha motor unit and all the skeletal muscle it innervates is collectively known as
A motor unit
What is the smallest component of the motor system
A motor unit
What does muscle contraction result from
The individual and combined action of motor units
The collection of alpha motor neurones that innervate a single muscle is known as
A muscle pool
What are the two mechanisms that control the force of muscle contraction
The frequency of action potential discharge of the motor neurone and the recruitment of additional, synergistic, motor units
Where are the cell bodies of alpha motor neurones found
The ventral horn
What are the three sources of input that regulate an alpha motor neurones activity
The central terminals or dorsal root ganglion cells, the upper motor neurones and the spinal interneurones
What do the axons of the central terminals/dorsal root ganglion innervate
The muscle spindle
Small motor units are involved in
Fine motor control
What are large motor units involved in
Large postural muscles
What are small motor units innervated by
Small alpha motor neurones
What are large motor neurones innervated by
Large alpha motor neurones
What is the fore of contraction dependent on
The size of the motor unit
What are the two types of motor units
Fast and slow
Fats and slow motor units contain
Muscle fibres of only one type
What are they types of muscle fibres involved in fast and slow motor units
Rapidly fatiguing or slowly fatiguing
Lower motor neurones innervating fast type motor units tend to be
Larger and have faster conducting axons than those of slow units
Where is each muscle fibre innervated
At the end plate (which is usually at the centre of the fibre)
Each muscle fibre is innervated by
A single motor axon
What does muscular strength depend on
The neuromuscular activation and the force produced by innervated muscle fibres
The neuromuscular activation involves
The firing rate of LMNs, the number of LMNs and the coordination of the movement
The force produced by innervated muscle fibres is dependent on
The fibre size (hypertrophy) and the fibre phenotype (fast or slow contracting muscles)
What does the frequency summation of a muscle fibre contraction affect
The neuromuscular activation
What does a single action potential in an alpha motor neurone cause
The muscle fibre to twitch
What does a summation of twitches cause
A sustained muscular contraction
What is an increase in the force due to
Temporal summation of individual fibres/motor units and then the recruitment of more motor units
The velocity of the contraction is due to
The muscle fibre type and the load on the muscle
The two main types of skeletal muscle are
Fast and slow
How do fast and slow skeletal muscle differ
In how fast myosin ATPase splits ATP to provide energy
How is the difference in fast and slow skeletal muscle reflected
In the time taken to reach peak tension
Characteristics of slow oxidative (type I) fibres
ATP derived, slow contraction/relaxation, fatigue resistant and have a high myoglobin content
What are the two types of fast fibres
Type IIa and type IIx (type IIb or glycolytic)
Characteristics of type IIa
ATP derived, fast contraction/relaxation rates, fatigue resistant, highly vascularised and high in myoglobin
Characteristics of type IIx
ATP derived, fast contraction rates, not fatigue resistant, poorly vascularised and high in glycogen
How are type I and type IIa fibres derived of ATP
Through oxidative phosphorylation
How are type IIx fibres derived of ATP
Through glycolysis
What are the three types of motor units
Slow (S), fatigue resistant (FR) and fast fatiguing (FF)
Characteristic of alpha motor neurones of the slow motor units
Small and have a low threshold
Characteristic of alpha motor neurones of the fast fatiguing motor units
Large and have a high threshold
Characteristics of a fast fatiguing motor unit
Very high tension, large alpha motor unit and type IIx fibres
Characteristics of a fatigue resistant motor unit
High tension, slow fatiguing, intermediate alpha motor neurone and type IIa fibres
Characteristics of a slow motor unit
Low tension, fatigue resistant, small alpha motor units and type I fibres
What is the Henneman size principle
The susceptibility of a motor neurone to discharge action potentials as a function of its size