Lecture 7 (Food Poisons) Flashcards
what is effect of 1 ppm diethylstilbestrol in utero?
increases adult obesity
what is characteristic of the western diet?
high in carbs and fats
what is the major site for nutrient absorption?
GI tract
trillions of microflora for digestion
what is the FDA tolerance?
unavoidable contaminants even w/ good manufacturing process
risk of harm deems food unfit
established limits (ex. aflatoxins)
FDA balanced with managing risks w/ loss of food supply
what are GRAS foods?
generally recognized as safe
are color additives eligible for GRAS?
no
how can food ingredients be made exempt and count as eligible for GRAS?
if sole purpose is not color
is chocolate to chocolate milk eligible for GRAS?
yes
is beet juice to color pink lemonade eligible for GRAS?
no
dietary supplements:
what are they?
ingredients must have food origin
different standard than food
grandfathered
burden of proof and lack of safety is FDA’s responsibility
dietary supplements:
how are they regulated?
> 60,000 on the market (2011)
many new FDA filings
70% of filings are incomplete
dietary supplements:
why are they a concern?
concentration
content
what was the disease in Guam caused by?
cycads
what happened in the Guam disease?
high rates of ALS w/ PD symptoms
source of disease from cycad seed kernel –> eaten by bats –> people eat bats and then get disease
what is toxic in cycad seed kernels?
beta-N-methylamino-L-alanine (BMAA)
cycasin
methylazoxymethanol
