Lecture 6: Lipids Flashcards

1
Q

Saturated Fatty Acid structure component

A

-single carbon bonds

-packs together

-solid at room temperature

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Unsaturated Fatty Acid structure component

A

-One or more double carbon bonds, fewer hydrogens

-don’t pack together

-liquid at room temperature

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Monounsaturated Fatty Acid structure component

A

one double carbon bond

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Polyunsaturated Fatty acid structure component

A

Two or more double carbon bond

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Methyl group

A

“Omega end” -CH3

3 carbons away from double bond
(omega-3 fatty acid)

6 carbons away from double bond (omega-6 fatty acid)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Omega-3

A

-Reduces inflammation, blood pressure & clotting

-a-linolenic acid (18 carbon)

-Eicosapentaenoic acid (EPA), (20 carbon)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Dietary source of Omega-3

A

Fish oils

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Omega-6

A

-Linoleic acid (18 carbons)

-polyunsaturated

-increases inflammation, blood pressure and blood clotting

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Dietary sources of Omega-6

A

vegetable oils, meats

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Essential fatty acids

A

A-linoleic & linoleic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Hydrogenation

A

H atoms are added to unsaturated fatty acids (cis) and create trans fatty acids.

Makes oils more solid (saturated)

reduces oxidation, rancidity and increases risk of CVD

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

CIS oleic acid (unsaturated fatty acid)

A

two functional groups on same side of the fatty acid chain

bends, does not pack tightly together

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Trans oleic acid (unsaturated fatty acid)

A

Functional groups on opposite sides of the double bond

chain is straight, easier to pack

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Carboxyl end

A

-COOH

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Types of lipids

A

Triglycerides (95%)
sterols (3%)
Phospholipids (2%)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Triglycerides function

A

-control the body’s internal climate

-help the body produce & regulate hormones

-main form of lipid in the body

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Leptin

A

Adipose tissues secretes this hormone, which regulates appetite

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Triglyceride structure

A

Glycerol joined by three fatty acids that consist of carboxylic acid (-COOH) and methyl group (-CH3)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

How do fatty acids differ

A

carbon chain length, degree of saturation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

how are fatty acids held together

A

carbon atoms attached to hydrogen atoms

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

What fatty acid is essential for normal cell development and healthy skin?

A

polyunsaturated and monounsaturated

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

Phospholipid structure components

A

-glycerol head/backbone containing phosphate group and nitrogen (hydrophilic)
-two fatty acid chains (hydrophobic)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

Phospholipids

A

essential components of cell membranes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

Most well-known sterol

A

cholesterol

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

Sterol

A

complex molecules that contain interlocking rings of carbon atoms with side chains of carbo, hydrogen and oxygen

26
Q

cholesterol functions

A

hormone functions, vitamin D synthesis

27
Q

Do we need cholesterol in our diet, why or why not

A

No, our body naturally produces cholesterol. There are no benefits and should be limited to 300mg/day

28
Q

What enzyme breaks down fat

A

Pancreatic lipase

29
Q

Pancreatic lipase

A

breaks down triglycerides into monoglycerides, fatty acids and glycerol

30
Q

Micelle

A

Transports lipids to SI surface for absorption

carriers that transport the hydrophobic lipids (such as triglycerides, cholesterol, and fat-soluble vitamins) to the surface of the intestinal epithelial cells (mucosal cells)

31
Q

Mucosal cells

A

Breaks down fat into glycerol, monoglycerides and fatty acids

the absorbed lipids are reassembled into triglycerides and packaged into chylomicrons within the mucosal cells

32
Q

Chylomicrons

A

lipid transport particle, enters lymph vessel

33
Q

Lipoproteins

A

Chylomicron, VLDL, LDL, HDL

34
Q

VLDL

A

formed by the liver after chylomicron delivers it’s content to the liver

35
Q

LDL

A

formed when VLDL loses triglycerides

delivers cholesterol to cells

36
Q

HDL

A

collects cholesterol from the cells back to the liver

37
Q

Eicosanoids

A

made of 20-carbon polyunsaturated fatty acid

38
Q

roles of lipids in health

A

energy storage

insulation & protection

hormone production

absorption of fat-soluble vitamins

39
Q

atherosclerosis

A

arteries become stiffer and plaque filled, lesion in heart artery

40
Q

AMDR for fat

A

20-35%

41
Q

AMDR for essential fatty acids

A

linoleic: 5-10%

a-linoleic: 0.5-1.2%

42
Q

dietary components of monounsaturated and polyunsaturated fats

A

olive oil, avocados, nuts, seeds, fatty fish

43
Q

unhealthy fats

A

saturated or trans fat

44
Q

healthy fats

A

unsaturated

45
Q

Where does lipid absorption take place?

A

Blood vessels and lymphatic system

46
Q

Adipose Tissue

A

How the body stores excess energy from food

47
Q

What reduces LDL and increases HDL

A

trans fat

48
Q

What should you add to rice to consume the essential amino acids? Broccoli or lentils?

A

Lentils

49
Q

Micelle structure function

A

fatty acid core with water-soluble exterior allowing efficient transportation to intestinal microvillus

50
Q

What are lipoproteins primarily made up of

A

triglycerides and cholesterol

51
Q

what dietary components decrease blood cholesterol

A

soluble Fiber
fatty fish, nuts, olive oil
moderating alcohol intake

52
Q

dietary sources of saturated

A

some meat, whole-sat dairy products and topical oils

53
Q

dietary sources of trans fat

A

processed cookies, pastries, friend food, margarines

54
Q

eicosanoids primary function

A

regulate inflammation

55
Q

health affects of trans fat

A

inflammation, cvd risk

56
Q

dietary-fat substitutes

A

carbohydrate-based replaces, can also be made from proteins (egg white, milk whey), not very stable can affected by temperature changes

57
Q

food labels and trans fat

A

allow foods containing trans fat to be labeled “trans-fat free” if there are fewer than 0.5 grams per serving

58
Q

what does cooking in vegetable oil refer to

A

hydrogenated vegetable oil: trans fat

59
Q

risk factors for disease

A

high bp, high cholesterol, smoking, diabetes, poor diet

60
Q

What does high LDL and low blood HDL indicate

A

blood cholesterol risk

61
Q

what can a buildup of cholesterol in the blood lead to?

A

brittle blood vessels and blockage of flow

62
Q

Lipid healthy diet includes:

A

choosing unsaturated fats, limiting saturated fat intake, low fat does not equal healthy, consume omega-3 daily, a “better fat” diet will support weight loss