Lecture 6

Question 1

Extracellular Matrix

Answer 1

Network of fibres that connect cells

Question 2

Collagen

Answer 2

Long chain of quaternary structure, forms structure of ECM, connects cells over long distances, cells organize on collagen scaffold

Question 3

Fibronectin

Answer 3

Links collagen to integrins

Question 4

Integrins

Answer 4

Proteins that span bilayer and link extracellular matrix to cytoskeleton

Question 5

Epithelial Layer

Answer 5

Layer of cells between you and your environment, can be one layer or multiple layers

Question 6

Apical Surface

Answer 6

Outsider of body

Question 7

Basal

Answer 7

Inside body, blood and lymph

Question 8

Tumour

Answer 8

Mass of cells growing out of control in a location they shouldn’t be, arise from unregulated cell division, requires an accumulation of mutations

Question 9

Tight Junctions

Answer 9

Right at apical barrier, function as rivets holding layers together, seal cells together and prevent passage of molecules between cells and environment

Question 10

Desmosomes

Answer 10

Distribute a stretching force across a tissue, connect adjacent cytoskeletons by intermediate filaments

Question 11

Gap Junctions

Answer 11

Basal lateral junctions, provide non-selective transport of small molecules between adjacent cells, sharing of nutrients, signals and cytoplasm

Question 12

Interrelated Disk

Answer 12

Structure between heart muscle cells