Lecture 4 Cardiac function B6

Question 1

What happens to stroke volume if ESV got larger?

Answer 1

Lower

Question 2

During which stage of the cardiac cycle is ventricular pressure falling and all valves are closed.

Answer 2

Isovolumic relaxation

Question 3

All of cardiac cycle on a graph.

-usually the left side of heart

Answer 3

Wigger’s diagram

-Electrical changes always precede mechanical

Question 4

You can alter Cardiac output by what two things?

Answer 4

Heart rate: Easiest way, chronotropes
Stroke Volume: altering preload (Frank-Starling)
-altering afterload (force-velocity)
-contractility

Question 5

What is calcium sensitivity, or how well the heart pumps?

Answer 5

Contractility

Question 6

Changing preload - Frank Starling

What happens to EDV and ESV?

Answer 6

Beat to beat regulation… All you eject is the extra volume
Heart will pump exactly what it is given
EDV changes, but ESV stays the same

Question 7

Changing afterload- Force velocity

What happens to EDV and ESV?

Answer 7

EDV stays the same, ESV changes

Question 8

Anything that changes contractility.

Answer 8

Inotrope

Question 9

What is contractility?

Answer 9

Contractility is increase in overall performance at any preload.

Question 10

End diastolic volume is what?

Answer 10

PRELOAD

Question 11

Predict the effect of a negative chronotrope of diastolic filling time

Answer 11

Increased

Question 12

If the ESV is 50mls and the EDV is 150 mls what is stroke volume?

Answer 12

100

Question 13

If the ESV is 50mls and the EDV is 150 mls and heart rate in 100bpm what is cardiac output?

Answer 13

10,000 ml/min