Capillary filtration B6 Flashcards
___________ allow for exchange of cargo between blood and tissues
Capillaries
Nutrients, oxygen, electrolytes in
Wastes out
___________ allows for diffusion of small solutes and water.
Endothelium
usually no proteins or cells
Filtered fluid becomes the _____________
interstitial fluid
Non pemeable cross between endothelium at pores= _________.
Diffuse across the endothelial cells if permeable= ____________.
Paracellular
Transcellular
Pore size vary depending on organ…
___________ very small
___________ very large
Brain and eye
Kidney and liver
___________ are basically drain pipes, that drain interstitial fluid, thin walled, large pores and one way valves. Drains back into subclavian veins
Lymphatics
Lymph is propelled by contraction of ________________.
surrounding muscle
Process by which blood plasma is filtered across the capillary membrane to make the interstitial fluid
Ultrafiltration
There are 4 factors for ultrafiltration what are they?
Capillary pressure and interstitial fluid pressure (these fluctuate to control blood pressure)
Plasma colloid osmotic pressure and Interstitial fluid colloid osmotic pressure (albumin)
Plasma oncotic pressure
Inside vessel pulling blood in
Changes to venous resistance affects filtration more than arteriolar.
Arteriolar flow and venule flow
Diffusion of small or soluble molecules is only limited by blood flow…
Flow limited- equilibrates quickly
Large or insoluble molecules are limited by pore size.
Diffusion limited- equilibrates slowly or not at all
Distance to cell matters
To increase tissue concentration of flow limited molecules you must _________________
increase blood flow
To increase tissue concentration of diffusion limited molecule you must _______________
Increase diffusion rate
