Lecture 4 - Bioinformatics Flashcards
1
Q
In the Blosum-62, what is indicated by a - number when substituting amino acids?
A
Dissimilar substitution (different chemistries)
2
Q
Substitution introduces AA that is similar in size/chemical properties as the substituted AA
A
Conservative
3
Q
Substitution introduces AA that is not similar in size/chemical properties as the substituted AA
A
Non-conservative
4
Q
How many points are awarded for a similar amino acid in the sliding analysis of AAs?
A
+10
5
Q
How many points are added to gaps in sliding analysis of AAs?
A
-10
6
Q
In the Blosum-62, what is indicated by a + number when substituting amino acids?
A
Similar amino acids (regarding chemistry)