Lecture 4 - Bioinformatics Flashcards

1
Q

In the Blosum-62, what is indicated by a - number when substituting amino acids?

A

Dissimilar substitution (different chemistries)

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2
Q

Substitution introduces AA that is similar in size/chemical properties as the substituted AA

A

Conservative

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3
Q

Substitution introduces AA that is not similar in size/chemical properties as the substituted AA

A

Non-conservative

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4
Q

How many points are awarded for a similar amino acid in the sliding analysis of AAs?

A

+10

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5
Q

How many points are added to gaps in sliding analysis of AAs?

A

-10

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6
Q

In the Blosum-62, what is indicated by a + number when substituting amino acids?

A

Similar amino acids (regarding chemistry)

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