Lecture 17 - Membranes II

Question 1

Plasma membrane fluidity is controlled by:

a) fatty acid composition
b) saturation of fatty acids
c) position of double bonds
d) all of the above

Answer 1

d) all of the above

Question 2

Which provides more membrane fluidity, cis double bonds or trans double bonds?

Answer 2

cis (produces a bend)

Question 3

Fatty acids with longer tails have a ____ melting point.

Answer 3

higher

Question 4

Cholesterol interacts with FA tails and promotes more membrane (fluidity/stiffness)

Answer 4

stiffness

Question 5

Which of the following will occur quickly after photo bleaching?

a) lateral movement of phosphlipids
b) rapid “flip-flop” from inner to outer membrane, or vice versa.

Answer 5

lateral movement

Question 6

This cell layer provides signalling functions, cell adhesion functions, and cell identification functions.

Answer 6

glycocalyx

Question 7

Which membrane of the mitochondria is permeable to most substances?

Answer 7

outer membrane

Question 8

This structure allows for movement in and out of the nucleus

Answer 8

nuclear pore

Question 9

Which of the following is not a function of plasma membranes?

a) uptake of molecules
b) transport of molecules
c) degredation of phagocytized molecules
e) release of molecues

Answer 9

degredation of phagocytized molecules

Question 10

What protein is important in endocytosis?

Answer 10

clathrin

Question 11

Fusion of membrane bound vesicles to a synaptic neuron are assisted by what protein?

a) FRAP
b) SNARE
c) SOD-1
d) Calmodulin

Answer 11

SNARE

Question 12

Which of the following is required for proper inner mitochondrial membrane fusion?

a) formation of mitochondria to mitochondria “cross bridges”
b) large electrochemical gradient
c) large [GTP]
d) B & C

Answer 12

D) B & C

Question 13

This process salvages components of the mitochondria. It requires a sufficient electrochemical gradient and high [GTP] for hydrolysis.

Answer 13

mitochondrial fusion

Question 14

This “sorts” mitochondria to newly formed daughter cells.

Answer 14

mitochondrial fission

Question 15

Transport of proteins from ribosomes into the mitochondria is mediated by what protein set?

a) GroEL/GroES
b) HSP-90
c) HSP-70
d) . Tim/Tom System

Answer 15

D) Tim/Tom system

Question 16

Matrix targeting signals for protein translocation into the mitochondrial matrix are located on the ____ end of the nascent protein.

a) C-terminus
b) N-terminus
c) HSP-70 protein
d) Ribosome

Answer 16

B) N-terminus

Question 17

Amyloid plaques in mitochondria are a hallmark of this neurodegenerative disease

Answer 17

Alzheimer’s

Question 18

Destruction of dopaminergic neurons are a hallmark of this neurodegenerative disease.

Answer 18

Parkinson’s

Question 19

Abnormal trafficking of mitochondria away from the neuronal end are a hallmark of this disease.

Answer 19

Huntington’s

Question 20

Impairment of the electron transport chain proteins are found in this disease:

a) Alzheimer’s
b) Krutzfeldt-Jakob disease
c) Parkinson’s
d) Huntington’s

Answer 20

C) Parkinson’s

Question 21

Decreased inner mitochondrial proteins are found in this disease.

Answer 21

Alzheimer’s disease