Lecture 39 - Learning and Memory - AMPA-R Flashcards
Explicit memory of facts, events, people, etc. Located in the temporal lobe.
A. Declarative
B. Procedural
A. Declarative
Sustained action potentials that remain long after NT release
Long Term Potentiation
Memory for perception and mental operations.
A. Declarative
B. Procedural
B. Procedural
Long term potentiation is induced by the NT _____ in the hippocampus.
A. Asparagine
B. Nitric oxide
C. Glutamate
D. Tyrosine
C. Glutamate
Low frequency stimulation of the NMDA receptor produces small amounts of Ca2+ influx. This acts to _____ Inhibitor-1 through ______.
A. activate; maintaining phosphorylation
B. activate; maintaining dephosphorylation
C. deactivate; maintaining phosphorylation
D. deactivate; maintaining dephosphorylation
B. activate; maintaining dephosphorylation
This receptor is translocated to the membrane with high amounts of Ca2+ influx.
AMPA
Large amounts of Ca2+ that influx through the NMDA receptor activate _____.
a. Calcineurin
b. Inhibitor-1
C. Adenylate cyclase
C. adenylate cyclase
Adenylate cyclase produces large amounts of _____, which directly activates _____.
a. cAMP; Inhibitor-1
b. cAMP; PKA
c. CamK; Inhibitor-1
d. Calcineurin; PKA
b. cAMP; PKA
PKA is responsible for the dephosphorylation of _____.
PP-1
Autophosphorylation of ____ produces translocation of the AMPA receptor to the PM.
CamK
Draw the low frequency path of synaptic plasticity.
Check drawing
Draw the high frequency path of synaptic plasticity.
check drawing
During surgeries in epileptic patients, the _____ was stimulated, evoking memories thought repressed.
A. Cortex
B. Medulla
C. Hippocampus
D. Pontine nucleus
C. hippocampus
