Lecture 33: Upper GI Histology II Flashcards
Gastric glands
Simple branched tubular glands with narrow isthmus opening through pits and base of gland extending into lamina propria
Mucous neck cells
Secrete soluble mucous (note: different from goblet cells)
Stem cells
Replace other cells in gastric pit due to rapid turnover of cells in the stomach
Chief cells
Secrete pepsinogen
Parietal cells
Manufacture HCl and secrete intrinsic factor
Enteroendocrine cells
Secrete hormones and serotonin
What features of the GI tractincrease surface area?
Size of small and large intestine, plicae circulares, villi, and microvilli
Microvillus
Contain glycoproteins and glycocalyx; bundles of actin cross-linked to each other and webbed to plasma membrane for support
Glycocalyx
Array of brush-border enzymes (maltase, sucrase, ismaltase, etc.) produced by small intestinal cells