Lecture #3: Digestive System Flashcards
How does the ancestral diet compare to a modern diet?
Ancestral diet had:
- less sugar
- more protein
- more natural food (less added preservatives)
- less salt
- more fiber
Catabolism
Breakdown of structure by enzymatic hydrolysis
• enzymatic hydrolysis: enzymes and water
Anabolism
Build up of structure
Calorie containing molecular
Proteins, carbohydrates, lipids
Proteins break down into?
Polypeptides, then animo acids
Carbohydrates break down into?
Polysaccharides, then monosaccharides (ex: glucose, fructose)
Lipids break down into?
Glycerol + 3 fatty acid chains
What does saliva do?
- Moistens food
- Antimicrobials
- Begin carb digestion
- amylase = enzyme for breaking down starch
What is the stomach and what does it do in the digestion process?
Acidic (PH (~ 2))
1. Begin protein breakdown
- Pepsin : enzyme for protein breakdown (works at a low ph)
• Cells store and release pepsinogen (less degrading)
• cells also release hydrochloric acid (HCl)
- turns pepsinogen into pepsin (active form of enzyme)
peptic ulcer - break in epithelial lining of stomach
• cause is bacteria infection
Acid reflux : Burning of lining of esophagus (heartburn)
What is the small intestine and what does it do in the digestion process?
3 parts of small intestine:
- durdeum (start of small intestine, more breakdown here, less adsorption)
- jejunun (middle of small intestine)
- ileum (end of small intestine, less breakdown here, more adsorption)
What is at the Junction of stomach + small intestine?
- pyloric sphinctur - controls release of material into small intestine
- Pancreas: produces bicarbonate to neutralize acid
- PH ~7
What is trypsin?
Trypsin is an enzyme that helps break down protein, works at a ph of ~ 7
8 essential amino acids
- must be in diet
- other 12 can be manufactured by body
- no plant food has all 8
- mix grain and legume (green peas, lentils, beans) and get all 3
How is digestion finished?
More amylases are added such as lactase
What is lactase?
Enzyme that breaks down lactose
- lactose = milk sugar
- produced in large quantities in juveniles (humans)