Lecture 29 Lipids 1 Flashcards
Beta oxidation occurs where?
mitochondrial matrix
FA activation occurs where?
cytosol
3 ketone bodies
acetoacetate
acetone
D-3-hydroxy-butyrate
diabetic ketosis
low blood pH
glucose unable to enter cells
ApoE
recognized by receptors on surface of liver cells allowing endocytosis
ApoCII
activates lipoprotein lipase (LPL) present on capillary endothelial cells, digest chylomicrons
FA beta oxidation steps
oxidation, hydration, 2nd oxidation, breakdown (thiolysis)
PUFA degradation of odd chains needs what enzyme(s)
isomerase
PUFA degradation of even chains needs what enzyme(s)
isomerase and reductase
where else my FA beta oxidation occur?
peroxisomes, able to shorten length of FA
major apoprotein?
B48 made in liver, RER