Lecture 28 OXPHOS Flashcards
F0
C ring, b2, a
embedded in inner mitochondrial membrane
F1 (ATPase/ATP synthase)
alpha, beta, gamma, delta, epsilon
resides in the matrix
Rotor units
c ring, gamma, epsilon
Stationary units
alpha, beta, delta, b2, a
Mitochondrial matrix characteristics
very negative, high pH, PDH lives here, beta oxidation of FA’s occurs here, urea cycle happens here
Inner membrane characteristics
impermeable to most everything except O2, CO2, H2O, NH3, ETC happens on this membrane
low pH
lots of [H+]
Flavin proteins
FMN, FADH2
what are cytochromes
Heme containing protein, have poryphirin ring structure w/Fe in the middle
Fe can reversibly bind electrons
Complex I name
NADH-Q oxidoreductase
NADH supplier, Q receiver
Complex 2 name
Succinate - Q reductase
FADH2 supplier
Q receiver
Complex 3 name
Q-cytochrome c oxidoreductant
Q supplier
cytochrome C receiver
Complex 4 name
Cytochrome C oxidase
cytochrome c supplier
O2 receiver