Lecture 21 Metabolism Intro

Question 0

E2

Answer 0

24 chains, lipoamide, transfer of acetyl group to CoA

Question 1

E1 (how many chains, prosthetic group, reaction catalyzed)

Answer 1

24 chains, TPP, oxidative decarboxylation of pyruvate

Question 2

E3

Answer 2

12 chains, FAD, Regeneration of oxidized form of lipoamide

Question 3

Sirtuin 3 found where?

Answer 3

mitochondria

Question 4

Sirtuin 1 found where?

Answer 4

nucleus

Question 5

Order the following compounds from most energy released by oxidation to least energy released:
formaldehyde, carbon dioxide, formic acid, methanol, methane,

Answer 5

methane > methanol > formaldehyde > formic acid >carbon dioxide

Question 6

How are metabolic processes regulated in 3 ways?

Answer 6

amt of enzyme (transcription/signaling)
catalytic activity (feedback inhibition)
accessibility of substrates (pathway compartmentalization)