Lecture 25 - Cell damage II

Question 1

What is the difference between necrosis and apoptosis?

Answer 1

Apoptosis is programmed, necrosis is death due to adverse external events

Question 2

When is apoptosis important?

Answer 2

Organogenesis, metamorphosis, endocrine tissue, the immune system, tissue turnover

Question 3

Compare the histology of apoptosis and necrosis

Answer 3

Apoptosis: single cell affected, tissue structure unaffected
Necrosis: sheets of cell dying, tissue architecture disrupted

Question 4

What is the difference in cytology of apoptosis and necrosis?

Answer 4

Apoptosis: cell contract
Necrosis: cell swells

Question 5

What are the difference in tissue effects in apoptosis and necrosis?

Answer 5

Apoptosis: no inflammation
Necrosis: acute inflammatory reaction and disturbance of surrounding tissue

Question 6

Atrophy =

Answer 6

shrinkage in the size of the cell by the loss of cytoplasmic substance

Question 7

Hypertrophy =

Answer 7

increase in the size of cells and, as a result, to an increase in the size of the tissue

Question 8

Hyperplasia =

Answer 8

increase in the number of cells in an organ or tissue

Question 9

Aplasia =

Answer 9

no growth

Question 10

Metaplasia =

Answer 10

change to another phenotype of the same cell

Question 11

Dysplasia =

Answer 11

change to another phenotype that doesn’t match the tissue

Question 12

Where is hypertrophy prominent?

Answer 12

Muscle tissue