Lecture 24 - Cell damage I Flashcards
1
Q
What causes hypoxic injury?
A
A reduction in oxygen delivery -> ischaemia
2
Q
Necrosis =
A
cell death from an adverse external event, usually accidental and detrimental
3
Q
What are the 4 types of necrosis?
A
Coagulation, liquefaction, caseous, gangrenous
4
Q
What is coagulation necrosis?
A
Denaturation of all cytoplasmic proteins including the proteolytic enzymes leading to an immune response
5
Q
What is liquefaction necrosis?
A
Proteolytic enzymes convert the necrotic tissue to a fluid consistency
6
Q
What is gangrenous necrosis?
A
Necrotic tissue which has been secondarily infected by saprophytic organisms
7
Q
What are the 3 types of gangrenous necrosis?
A
Wet, dry, gaseous
8
Q
What are the 3 critical components of cellular function?
A
Boundary functions, energy metabolism and protein synthesis
