Lecture 24: Synaptic Networks Flashcards

1
Q

Different types of neurotransmitters:

A
  • Acetylcholine (ACh)
  • Glutamate (EPSP)
  • GABA (IPSP)
  • Norepinephrine / Noradrenaline
  • Dopamine
  • Serotonin
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2
Q

Methamphetamine increases levels of….

It also blocks …. It lingers in the synaptic cleft. Also acting in the ____ _____, making it highly addictive.

A
  • Noradrenaline
  • Dopamine
  • Serotonin
  • Reuptake
  • Reward centres
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3
Q

Almost all drugs target endogenous (______) systems.

A
  • Receptor
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4
Q

Excitatory causes ______

A
  • Depolarisation
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5
Q

Acetylcholine activatea stimulus-gated _____ channeles

A
  • Na+
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6
Q

Inhibitory causes ______

A
  • Hyperpolarisation
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7
Q

GABA activates _____ and ______ channels. This causes hyperpolarisation. (IPSP)

A
  • Cl-

- K+

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8
Q

Can one cell have excitatory and inhibitory synapses?

A
  • YES
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9
Q

EPSP =

IPSP =

A
  • BLEEP (RMP)

- BLOOP (RMP)

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10
Q

Local Synaptic Potentials (EPSPS + IPSPS) summate at the ___ ___, and an action potential is either generated or not.

A
  • Axon hillock
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11
Q

EPSP + EPSP =

A
  • Big EPSP (larger depolarisation)

- AP generation all depends on threshold being reached or not

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12
Q

EPSP + IPSP =

A
  • Nothing (they eliminate each other)

- AP generation all depends on threshold being reached or not

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13
Q

What is spatial summation?

A
  • We receive different signals at different sides of a neuron, at the axon hillock, both signals are summated
  • Signals come from DIFFERENT places
  • AP is generated if neuron is above threshold
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14
Q

What is temporal summation?

A
  • Signals arriving at the same synaptic knob within a short time range of each other integrate
  • Takes more time for repolarisation of local potentials if an AP is generated
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15
Q

What happens if excitatory and inhibitory signals arrive at the same time?

A
  • AP generation all depends on threshold being reached or not
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16
Q

Describe the divergence network:

A
  • Something where one signal from one neuron is being transmitted to more than one neuron
  • A single neuron DIVERGES to multiple neurons
  • Opportunity to amplify signals
  • Few control points
17
Q

Describe the convergence network:

A
  • Multiple neurons CONVERGE to a single neuron that initiates a single response
  • If you’re preparing dinner and you cut yourself you can either know you’ve cut yourself by seeing that you’ve cut yourself or the pain receptors let you know
  • Back-up route, multiple neurons converge to a single neuron to move away hand that’s holding knife :D