lecture 24 - GI motility and physiology Flashcards

1
Q

what do receptors in the wall of the GI tract respond to

A

stretch, change in composition, ph, osmolarity, amino acids, sugars and fats

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2
Q

what do reflexes (stimulated by receptors) in the GI tract stimulate

A
  • smooth muscle contraction
  • gland secretion
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3
Q

what does the parasympathetic nervous system do in the GI tract

A

stimulates motility and secretion

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4
Q

what does the sympathetic nervous system do in the GI tract

A

inhibits motility and secretion

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5
Q

what does the submucosal plexus do in the enteric nervous system

A

regulation of secretion

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6
Q

what does the myenteric plexus do in the enteric nervous system

A

regulation of motility

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7
Q

is the enteric nervous system self contained

A

yes

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8
Q

what is endocrine hormonal regulation in the GI tract

A

signalling using circulatory system to transport signals

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9
Q

what is paracrine hormonal regulation in the GI tract

A

signalling acts on near by cells

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10
Q

what are tonic contractions

A

sustained contractions for minutes to hours (e.g sphincters)

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11
Q

what are phasic contractions

A

waves of contraction and relaxation, each wave lasting seconds (e.g peristalsis)

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12
Q

what is a motility pattern

A

any contraction or relaxation of GI tract smooth muscle
- some motility patterns can be a combination of two or more simpler patterns (e.g retropulsion)

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13
Q

what is GI tract motility like in terms of contraction

A

contracts without external input
- spontaneously active

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14
Q

what happens in the GI tract when you are fasting

A

housekeeping = removes residual secretions, removes undigested material, promotes epithelial cell turnover

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15
Q

what happens in the GI tract when you are in a feeding state

A

storage, propulsion and mixing

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16
Q

what part of the stomach is responsible for storage

A

fundus and body of stomach

17
Q

what part of the stomach is responsible for mechanical digestion and mixing

A

antrum

18
Q

what part of the stomach controls the delivery to the duodenum

A

pyloric sphincter

19
Q

what factors affect the rate of gastric emptying

A

size of the meal = larger the meal faster the emptying
composition of the meal = fluids faster than solids, fats and acids slow gastric emptying

20
Q

what is the function of motility in the small intestine

A
  • mixing with secretions from the pancreas
  • controlled movement / propulsion
  • exposure of products of digestion to absorptive surfaces
21
Q
A