lecture 22

Question 1

For Rabbit haemorrhagic disease virus list the clinical signs

Answer 1

Rabbit haemorrhagic disease virus clinical signs

• very contagious
• fatal in both wild and domesticated rabbits
• fever
• anorexia
• nervous signs (convulsion, ataxia, paralysis)
• respiratory signs (dyspnoea, frothy)
• cyanosis of mucous membranes

Question 2

Explain the different ways of transmission for Rabbit haemorrhagic disease virus

Answer 2

Rabbit haemorrhagic disease virus Transmission
direct contact through oral, nasal or conjunctival routes (most excretions contain the virus)
-exposure to infected carcass or hair from infected animal
-mechanical transmissions- flies and other insects
mechanical vectors only require a few virons to infect

Question 3

For Vesicular exanthema of swine virus list the clinical signs

Answer 3

Vesicular exanthema of swine virus clinical signs
disease is associated with vesicles in the mouth, tongue, lips snout and feet
-may cause encephalitis, myocarditis, fever, diarrhoea, abortion
vesicular fluid has high level of virus

Question 4

For Vesicular exanthema of swine virus explain diagnosis

Answer 4

Vesicular exanthema of swine virus diagnosis
vesicular fluid has high level of virus
ELISA- for ag detection
RT-PCR assays for RNA detection

Question 5

For Vesicular exanthema of swine virus discuss control

Answer 5

Vesicular exanthema of swine virus control
its controlled by test and slaughter
prevent occurs by no swill feeding

Question 6

For Feline Calicivirus explain pathogenesis

Answer 6

Feline Calicivirus pathogenesis

• shed in oral and nasal secretions during the acute phase of disease, some animals may shed the virus for years
• cats are infected via nasal, oral or conjunctival routes
• oral ulceration is very common
• pulmonary involvement is rare
• limping syndrome in acute phase this is because the virus infects macrophages and this will in turn infect the synovial fluid

Question 7

For Feline calicivirus list epidemiology

Answer 7

Feline calicivirus epidemiology
virus is shed in large amounts in the respiratory system, urine, faeces of infected cats
transmission occurs y aerosol route and via fomitess
recovery is followed by a prolonged oropharyngeal carrier
-virus survives in the environment and remains infectious up to 1 month

Question 8

For Feline calicivirus explain diagnosis (samples, tests)

Answer 8

Feline calicivirus diagnosis
conjuctival swabs, oral swabs, blood, skin, scrapings, lung tissue are the samples
RT-PCR can be used to detect
cell cultures can also be used

Question 9

For Feline calicivirus discuss vaccination

Answer 9

Feline calicivirus vaccination
reduces severity but can’t protect the animal completely
its a core vaccine

Question 10

For avian nephritis virus state the clinical signs, diagnosis, treatment

Answer 10

avian nephritis virus 
clinical signs diarrhoea, -growth retardation
-kidney damage
diagnosis; RT-PCR 
treatment; no treatment

Question 11

For Avian HEV list the clinical signs, pathology, diagnoses, prevention/control

Answer 11

Avian HEV
clinical signs and pathology can be variable
diagnoses 
RT-PCR viral RNA detection 
ELISA for ab detection 
there is no prevention or control