lecture 18

Question 1

For Feline immunodeficiency virus discuss epidemiology

Answer 1

Feline immunodeficiency virus epidemiology
is spread from cat to cat via saliva
cats which are roam outside, males and older cats are more likely to become infected.

Question 2

Feline immunodeficiency virus discuss pathogenesis

Answer 2

Feline immunodeficiency virus pathogenesis
all animals will be persistency infected
virus replicates in CD4 cells and levels of CD4 cells will decrease and the viraemia is high clinical signs can be showed and this animal has a comprised immune system

Question 3

For Feline immunodeficiency virus explain treatment and prevention

Answer 3

Feline immunodeficiency virus treatment and prevention
there is no effective treatment but supportive care and treatment of signs is important
to stop secondary infections, provide a balance diet, control tumours
all infected cats should be spayed and neutered
vaccination is available but its not core
its unstable in the environment and is susceptible to all common detergent and disinfectants

Question 4

How do you diagnosis Feline immunodeficiency virus

Answer 4

Feline immunodeficiency virus , diagnosis
detection of provirus DNA by PCR
detection of viral RNA by RT-PCR
detection of ab by ELISA or immunochromatography
may cause false negative from abs which are present for years

Question 5

For Equine infectious anaemia virus list the clinical signs

Answer 5

Equine infectious anaemia virus clinical signs
-the disease passes through clinal phases
acute episode is characterised by fever, depression and thrombocytopenia
initial phase is followed by a prolonged period with recurring episodes of fever, thrombocytopenia, anaemia
infected horse become inapparent carrier and reservoirs
donkeys are less likely to develop clinical signs

Question 6

For Equine infectious anaemia virus discuss pathology

Answer 6

Gross lesions, present in acute cases include enlargement of the spleen, liver and abdominal lymph nodes
chronic cases of infections have emaciation, pale mucous membranes

Question 7

For Equine infectious anaemia virus discuss laboratory detection

Answer 7

Equine infectious anaemia virus laboratory detection

• agar gel immunodiffusion
• ELISA
• use these tests in combination to get the highest level of sensitivity/ specificity

Question 8

How is Equine infectious anaemia virus controlled

Answer 8

Equine infectious anaemia virus control
horse which are moved should be tested before they enter new properties
there is no treatment or vaccine

Question 9

List the clinical signs of maedi visna

Answer 9

clinical signs of maedi visna
ill thrift
chronic respiratory disease
indurative mastitis
Maedi; wasting, progressive dyspnea
eventual death from secondary bacteria infection
Visna; neurological signs like hindlimb weakness, trembling of lips or head tilt, loss of condition

Question 10

For maedi visna explain pathology

Answer 10

maedi visna pathology
maedi;
lungs are enlarged, abnormally firm and heavy and fail to collapse when thoracic cavity is open
Visna:
focal asymmetric, pink areas in white matter of the brain and spinal cord

Question 11

List the clinical signs of Jaagsiekte sheep retrovirus

Answer 11

Jaagsiekte sheep retrovirus clinical signs
virus replicates predominatly in lung tumour cells, is release into the airway and is found in the respiratory secretion
tumours produce clinical signs

Question 12

List the clinical signs of Bovine leukaemia virus

Answer 12

Bovine leukaemia virus clinical signs
persistence with no outward signs of infection
persistent lymphocytosis , the cows will serve as a reservoir of infection and may pass infection to calves in utero