Lecture 19 Flashcards

1
Q

Heterogametic sex

A

Males XY

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2
Q

Homogametic sex

A

Females XX

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3
Q

Y chromosome

A

Not man genes on it but determines maleness in humans

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4
Q

X chromosome

A

Larger chromosome with a large number of genes on it

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5
Q

Sex linked genes on which chromosomes

A

X chromosomes

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6
Q

Non sex chromosomes called what

A

Autosomes

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7
Q

Barr body

A

Inactive condensed chromatin remains inactive for a cell- lines progeny

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8
Q

Females have 2 X chromosomes, while males have 1, what happens in women

A

One of the X chromosomes is always inactivated to form a barr body

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9
Q

X inactivation is a cell -line specific trait

Examples

A

Calico cats with orange and black patches result from inactivation of one of the 2 X chromosomes in the skin

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10
Q

SRY gene

A

Gene on the Y chromosome

Master switch that directs development of maleness at an early stage of embryonic development

Basically
Sex determining region of the Y chromosome

Gene codes for sex determining region Y protein

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11
Q

How long for SRY gene to become active

A

Male embryo the tissues that form reproductive structures don’t begin to differentiate into testes until SRY becomes active

6-8 weeks

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12
Q

Is the SRY a pleiotropic gene

Why

A

Yes

Affects many tissues in the embryo

Suppresses female differentiation

Also works to develop and maintain secondary sex characteristics in males

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13
Q

One of the best known X linked disorder

A

Hemophilia

Blood doesn’t clot normally, so any cut or bruise can be life threatening

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14
Q

How to do sex linked traits

A

Dominant H
Recessive h

X^H X^h cross them

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15
Q

Hemizygous

A

Only receive one copy of a sex linked gene

Presence of one normal allele will mean ur chilling

One bad one and ur cooked

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