Lecture 16-17 (Mutations, DNA Repair, HGT) Flashcards
Mutations in which of the molecules would have the most significant consequences?
A. mRNA
B. DNA
C. RNA
D. None of these
B.
Mutations from the DNA Poly III occur more frequently from base mismatches than slipped strand mispairing?
T/F
False
Which of the following would be the LEAST detrimental?
A. Misense Mutations
B. Nonsense Mutations
C. Frameshift Mutations
D. Silent Mutations
D.
DNA Poly III can fix base mismatches during replication using what activity?
3’ to 5’ Exonuclease activity
Which of the following point mutations results in a premature Stop Translation?
A. Misense Mutations
B. Nonsense Mutations
C. Frameshift Mutations
D. Silent Mutations
B.
The methyl-directed mismatch system (MMR) recognizes base mismatches how?
Physical Distortion to DNA Helix
The UvrABC system would more likely be fixing mutations from Mutagen damage because it detect chemically damaged bases.
T/F
True
Which of the following enzymes would be Least useful in response to Massive amounts of DNA damage from a mutagen?
A. DNA Poly IV
B. DNA Poly I
C. DNA Poly III
D. RNA Poly
C
Holiday Junctions are resolved using which protein(s)?
A. RuvA
B. RecB
C. RuvC
D. RuvABC
D.
A bacteriophage would likely switch from a lysogenic to a lytic life cycle when?
AFTER activation of RecA
What is Polarity?
It is a side effect of mutations within Operons
LexA is part of which DNA repair system?
A. SOS system
B. MDMR system
C. Recombination Repair
D. DNA Poly III proofreading
A.
- _____ recognizes & binds to distorted DNA, 2. ______ Links MutS & MutH, 3. _______ Endonuclease Distorted DNA in MDMR system.
- MutS
- MutL
- MutH
RecA binds to damaged bases & activates to what?
Rec*
What is the difference between RecFOR pathway and RecBCD pathway?
RecFOR pathway is for SIGNLE stranded Nicks/gap, while
RecBCD pathway is for DOUBLE stranded Nicks/Gaps.
