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Clinical Pharmacology > Lecture 15 - Time Course of Delayed Drug Effect > Flashcards

Lecture 15 - Time Course of Delayed Drug Effect Flashcards

1
Q

Delayed drug effects?

A

pharmaco-kinetics, receptor-kinetics, physio-kinetics

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2
Q

Equilibration Half-Life?

A

determined by two factors of the ‘effective compartment’ - volume (organ size, tissue binding) and clearance (blood flow, diffusion)

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3
Q

Digoxin volume and clearance?

A

extensive binding in heart to Na/K ATPase; rapid perfusion of heat - slow unbinding causes delayed onset

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4
Q

Irreversible Anti-Cancer Agent action?

A

irreversible binding to cell structure, block of cell division/death, slowing or reversal of tumour growth

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Clinical Pharmacology (21 decks)

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