Lecture 13 - Poisons Flashcards
1
Q
Diagnosis - pupil constriction?
A
opiates (morphine), clonidine, anti-cholinesterases (neostigmine)
2
Q
Diagnosis - pupil dilation?
A
atropine, tricyclic antidepressants, amphetamines
3
Q
Diagnosis - skin?
A
sweating (increased amphetamine, decreased atropine) bullae (carbon monoxide)
4
Q
Diagnosis - odour?
A
ethanol, arsanic or organophosphates (garlic smell), cyanide (almond smell)
5
Q
Methods of decreased absorption?
A
syrup of ipecac, activated charcoal, stomach pump
6
Q
Methods of increased elimination?
A
activated charcoal, haemoperfusion, haemodialysis
7
Q
Paracetemol Hepatotoxicity?
A
Minor metabolite NAPQI, causes liver dmage, inativated by glutathione, gltahione reserves used up in large doses, Acetylcysteine boosts production
